Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.39 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30919680 | 1.00 | BTK (0.46) | BTKADORA1MAP4K4CYP2A6RPS6KA5 | |
| SCHEMBL27264188 | 0.88 | ADORA1 (0.43) | BTKADORA1MAP4K4CYP2A6RPS6KA5 | |
| SCHEMBL30919849 | 0.88 | ADORA1 (0.43) | BTKADORA1MAP4K4CYP2A6RPS6KA5 | |
| SCHEMBL27263191 | 0.87 | BTK (0.43) | BTKADORA1MAP4K4RPS6KA5LMNA | |
| SCHEMBL30919676 | 0.87 | BTK (0.43) | BTKADORA1MAP4K4RPS6KA5LMNA | |
| SCHEMBL30919634 | 0.83 | ADORA1 (0.50) | BTKADORA1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30444276 | 0.83 | KDM4E (0.55) | BTKADORA1RPS6KA5LMNAALDH1A1 | |
| SCHEMBL25820968 | 0.83 | KDM4E (0.55) | BTKADORA1RPS6KA5LMNAALDH1A1 | |
| SCHEMBL29967741 | 0.82 | BTK (0.52) | BTKADORA1RPS6KA5LMNAALDH1A1 | |
| SCHEMBL30919617 | 0.82 | BTK (0.52) | BTKADORA1RPS6KA5LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |