Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.38 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30919676 | 1.00 | BTK (0.43) | BTKALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL30919863 | 0.89 | RPS6KA5 (0.40) | BTKALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL30919680 | 0.87 | BTK (0.46) | BTKALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL27263103 | 0.87 | BTK (0.46) | BTKALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL30919841 | 0.83 | BTK (0.46) | BTKALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL27263764 | 0.83 | BTK (0.46) | BTKALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL30919634 | 0.82 | ADORA1 (0.50) | BTKALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30444276 | 0.79 | KDM4E (0.55) | BTKALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL25820968 | 0.79 | KDM4E (0.55) | BTKALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL29967741 | 0.79 | BTK (0.52) | BTKALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107746-A1 | INHIBITORS AND DEGRADERS OF PIP4K PROTEIN | LARKSPUR BIOSCIENCES (US) | 2024-05-23 | — | — | WO | disclosed |