Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9022464 | 0.76 | CNR2 (0.46) | CNR1CNR2EPHX2KDM4ECA12 | |
| SCHEMBL9022900 | 0.76 | CYP2C19 (0.49) | DAOPRSS1TMPRSS15EPHX2LMNA | |
| SCHEMBL9022822 | 0.75 | MEN1 (0.43) | CNR1CNR2EPHX2KDM4EPPARG | |
| SCHEMBL12926197 | 0.74 | KDM4E (0.54) | EPHX2KDM4ELMNAALDH1A1MAPT | |
| SCHEMBL24434970 | 0.71 | KDM4E (0.43) | CNR1CNR2EPHX2KDM4EPPARG | |
| SCHEMBL9022216 | 0.71 | HDAC8 (0.57) | CNR1CNR2EPHX2KDM4EMEN1 | |
| SCHEMBL11490984 | 0.70 | LMNA (0.43) | CNR1CNR2EPHX2KDM4EPPARG | |
| SCHEMBL1607395 | 0.70 | CNR2 (0.57) | CNR2EPHX2KDM4ELMNAMAP3K14 | |
| SCHEMBL9029786 | 0.70 | L3MBTL1 (0.41) | CNR1CNR2EPHX2KDM4EPPARG | |
| SCHEMBL29229 | 0.69 | LMNA (0.44) | EPHX2PPARGLMNAMAP3K14MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1022754-C | Novel aryl-or heteroaryl-1-alkyl-pyrrole-2-carboxylic acid compounds preparation method | MERRELL DOW PHARMA (US) | 1993-11-17 | — | — | CN | disclosed |
| CN-1044653-A | The new aryl or the heteroaryl-I-alkyl-pyrroles-2-carboxylic acid that are used for the treatment of the pathological state of interleukin-I mediation | MERRELL DOW PHARMA (US) | 1990-08-15 | — | — | CN | disclosed |