Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 10/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31394558 | 0.87 | NOS3 (0.38) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL875673 | 0.85 | L3MBTL1 (0.57) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL31588436 | 0.84 | KDM4C (0.44) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL2317607 | 0.84 | KDM4C (0.48) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL6400712 | 0.82 | NPC1 (0.59) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL772902 | 0.81 | KDM4C (0.53) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL24252402 | 0.80 | KDM4C (0.46) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL9570948 | 0.78 | KDM4C (0.49) | KDM4CL3MBTL1NPC1RAB9AMEN1 | |
| SCHEMBL31588961 | 0.77 | KDM4E (0.41) | L3MBTL1KMT2ANOS3NOS1NOS2 | |
| SCHEMBL12963637 | 0.77 | NPC1 (0.47) | KDM4CL3MBTL1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120035598-A | Method for preparing PRMT5 inhibitor | 普莱鲁德疗法股份有限公司 | 2025-05-23 | — | — | CN | disclosed |
| EP-4540261-A1 | PROCESSES FOR MAKING PRMT5 INHIBITORS | Prelude Therapeutics Incorporated (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023245037-A1 | PROCESSES FOR MAKING PRMT5 INHIBITORS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2023-12-21 | — | — | WO | disclosed |
| WO-2023245037-A1 | PROCESSES FOR MAKING PRMT5 INHIBITORS | PRELUDE THERAPEUTICS INCORPORATED (US) | 2023-12-21 | — | — | WO | disclosed |