SCHEMBL27264154

SCHEMBL27264154

CCCC(=N)CC1CSCCN1C(=O)C1CC(=O)c2ccc(C)cc21

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
OPRK1 P41145 4/20 0.33
MAPT P10636 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30
SRD5A1 P18405 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27264601 0.93 ALDH1A1 (0.30) ALDH1A1HTT
Hydrochloric Acid SCHEMBL27501817 0.92
SCHEMBL27264216 0.90 OPRK1 (0.43) OPRK1SRD5A1
SCHEMBL27263921 0.89
SCHEMBL27264454 0.88 OPRK1 (0.32) OPRK1ALDH1A1
SCHEMBL27264883 0.88 MEN1 (0.36) OPRK1
SCHEMBL27263822 0.84 OPRK1 (0.36) OPRK1
Hydrochloric Acid SCHEMBL27324062 0.84 OPRK1 (0.36) OPRK1
SCHEMBL27264707 0.83 KDM4E (0.32) ALDH1A1
SCHEMBL27264667 0.82 ALDH1A1 (0.34) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1036004-C Process for preparing analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1997-10-01 CN disclosed
CN-1034731-C Process for preparing analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1997-04-30 CN disclosed
CN-1030450-C Preparation of analgesic carboxylic acid amides derivative SANKYO CO (JP) 1995-12-06 CN disclosed
CN-1079740-A The preparation method of analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-12-22 CN disclosed
CN-1079741-A The preparation method of analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-12-22 CN disclosed
CN-1078461-A The preparation method of analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-11-17 CN disclosed
CN-1022185-C Process for preparing analgesic carboxylic acid amide derivatives SANKYO CO (JP) 1993-09-22 CN disclosed
CN-1040791-A ANALGESIC CARBOXYLIC ACID AMIDE DERIVATIVES SANKYO CO (JP) 1990-03-28 CN disclosed