Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.49 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26582560 | 0.88 | NAMPT (0.45) | CACNA1BNAMPTGAAL3MBTL1HDAC1 | |
| SCHEMBL30608812 | 0.88 | NAMPT (0.45) | CACNA1BNAMPTGAAL3MBTL1HDAC1 | |
| SCHEMBL10233014 | 0.83 | ALDH1A1 (0.52) | CACNA1BNAMPTGAAL3MBTL1HDAC1 | |
| SCHEMBL27264491 | 0.83 | GFER (0.45) | CACNA1BNAMPTGAAL3MBTL1HDAC1 | |
| SCHEMBL26582552 | 0.83 | GFER (0.45) | CACNA1BNAMPTGAAL3MBTL1HDAC1 | |
| SCHEMBL12072841 | 0.82 | HTR2C (0.53) | NAMPTGAAL3MBTL1EPHX1FPR3 | |
| SCHEMBL6993991 | 0.81 | EPHX1 (0.59) | CACNA1BGAAEPHX1RAB9ASMN1; SMN2 | |
| SCHEMBL3180689 | 0.80 | L3MBTL1 (0.61) | NAMPTGAAL3MBTL1HDAC1FPR3 | |
| SCHEMBL507402 | 0.80 | HDAC6 (0.49) | CACNA1BNAMPTGAAL3MBTL1EPHX1 | |
| SCHEMBL1491536 | 0.79 | CACNA1B (0.51) | CACNA1BNAMPTGAAL3MBTL1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023201282-A1 | NOVEL GSPT1 COMPOUNDS AND METHODS OF USE OF THE NOVEL COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-10-19 | — | — | WO | disclosed |