Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | RHEB | Q15382 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30217304 | 1.00 | TRPA1 (0.33) | TRPA1RHEB | |
| SCHEMBL30805095 | 0.91 | TRPA1 (0.32) | TRPA1RHEB | |
| SCHEMBL27265232 | 0.91 | TRPA1 (0.32) | TRPA1RHEB | |
| SCHEMBL30750020 | 0.89 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL30750398 | 0.89 | TRPA1 (0.33) | TRPA1RHEB | |
| SCHEMBL30805052 | 0.89 | RHEB (0.31) | TRPA1RHEB | |
| SCHEMBL29336818 | 0.88 | TRPA1 (0.32) | TRPA1RHEB | |
| SCHEMBL31108560 | 0.88 | TRPA1 (0.32) | TRPA1RHEB | |
| SCHEMBL27382327 | 0.86 | TRPA1 (0.36) | TRPA1RHEB | |
| SCHEMBL30750320 | 0.86 | EGFR (0.33) | TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201919-A | Indole compounds and methods of use | 健赞公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2024054845-A1 | MACROCYCIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024054840-A1 | MACROCYCLIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |