Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | F7 | P08709 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30805095 | 1.00 | TRPA1 (0.32) | TRPA1RHEBF2F10PLAU | |
| SCHEMBL30750020 | 0.94 | TRPA1 (0.31) | TRPA1 | |
| SCHEMBL30805052 | 0.93 | RHEB (0.31) | TRPA1RHEB | |
| SCHEMBL27265135 | 0.91 | TRPA1 (0.33) | TRPA1RHEB | |
| SCHEMBL30217304 | 0.91 | TRPA1 (0.33) | TRPA1RHEB | |
| SCHEMBL31108560 | 0.86 | TRPA1 (0.32) | TRPA1RHEB | |
| SCHEMBL29336818 | 0.86 | TRPA1 (0.32) | TRPA1RHEB | |
| SCHEMBL31108473 | 0.86 | — | — | |
| SCHEMBL27265138 | 0.86 | — | — | |
| SCHEMBL30750451 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054845-A1 | MACROCYCIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |