Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.43 |
| ▸ | HTR3B | O95264 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 2/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.37 |
| ▸ | ATP4A | P20648 | 1/20 | 0.37 |
| ▸ | ATP4B | P51164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1772018 | 0.79 | MAPK8 (0.40) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL19036185 | 0.75 | MAPK8 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27244322 | 0.74 | DAO (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27244340 | 0.73 | KDM4E (0.50) | L3MBTL1 | |
| SCHEMBL12074764 | 0.73 | CCNE1 (0.43) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL29789954 | 0.73 | IKBKB (0.42) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13131265 | 0.72 | PTPN2 (0.59) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL27265681 | 0.72 | NPC1 (0.50) | L3MBTL1 | |
| SCHEMBL15479137 | 0.72 | PTPN1 (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL19606124 | 0.70 | HTR3E (0.41) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024107555-A1 | AHR AGONISTS | ELI LILLY AND COMPANY (US) | 2024-05-23 | — | — | WO | disclosed |