Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 5/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30962073 | 0.87 | PIK3CD (0.38) | PIK3CDPARP1NOTUMMAPK8MAPK10 | |
| SCHEMBL30962064 | 0.86 | NOTUM (0.48) | PARP1NOTUMMEN1ALDH1A1LMNA | |
| SCHEMBL27265692 | 0.81 | PARP1 (0.35) | PARP1NOTUMKDM4EALDH1A1HTR2C | |
| SCHEMBL27266069 | 0.79 | PIK3CD (0.42) | PIK3CDNOTUMMEN1KMT2AHTR2C | |
| SCHEMBL30962052 | 0.79 | NOTUM (0.42) | PIK3CDPARP1NOTUMKDM4EALDH1A1 | |
| SCHEMBL27265633 | 0.77 | NPC1 (0.34) | PARP1ALDH1A1 | |
| SCHEMBL2676013 | 0.71 | OPRM1 (0.48) | PARP1MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL2015572 | 0.71 | DRD2 (0.41) | PIK3CDKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL31134547 | 0.71 | PARP1 (0.38) | PARP1ALDH1A1HTR2CHTR2BHTR2A | |
| SCHEMBL30962102 | 0.70 | NOTUM (0.42) | PARP1NOTUMKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024130342-A1 | TRANSIENT RECEPTOR POTENTIAL VANILLOID 6 INHIBITORS | UNIQUEST PTY LIMITED (AU) | 2024-06-27 | — | — | WO | disclosed |