Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | NQO1 | P15559 | 3/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL28193011 | 0.98 | KIF11 (0.44) | KIF11HPRT1ALDH1A1CYP1A2LCK | |
| Pyrrole SCHEMBL27865761 | 0.98 | KIF11 (0.44) | KIF11HPRT1ALDH1A1CYP1A2LCK | |
| Pyrrole SCHEMBL28097212 | 0.98 | KIF11 (0.44) | KIF11HPRT1ALDH1A1CYP1A2LCK | |
| Piperazine SCHEMBL28106719 | 0.94 | KIF11 (0.41) | KIF11HPRT1ALDH1A1CYP1A2LCK | |
| Pyrrole SCHEMBL28177497 | 0.92 | KIF11 (0.40) | KIF11HPRT1ALDH1A1CYP1A2LCK | |
| Pyrrole SCHEMBL27416005 | 0.92 | KIF11 (0.40) | KIF11HPRT1ALDH1A1CYP1A2LCK | |
| Phenol SCHEMBL28182863 | 0.92 | ALDH1A1 (0.41) | KIF11HPRT1ALDH1A1CYP1A2LCK | |
| SCHEMBL2089665 | 0.90 | HPRT1 (0.54) | KIF11HPRT1ALDH1A1CYP1A2LCK | |
| SCHEMBL30928215 | 0.90 | HPRT1 (0.54) | KIF11HPRT1ALDH1A1CYP1A2LCK | |
| SCHEMBL21176632 | 0.90 | HPRT1 (0.54) | KIF11HPRT1ALDH1A1CYP1A2LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 705 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108699041-A | Novel imidazole derivatives and application thereof with JNK inhibitory activity | 三进制药株式会社 | 2018-10-23 | — | — | CN | claimed |
| CN-108699441-A | Liquid-crystal composition and liquid crystal display element | 捷恩智株式会社 | 2018-10-23 | — | — | CN | claimed |
| CN-108690024-A | A kind of piperazine Nino peace analog and its preparation method and application | 中国海洋大学 | 2018-10-23 | — | — | CN | claimed |
| CN-108699052-A | ANTHELMINTIC DEPSIPEPTIDE COMPOUNDS | 梅里亚股份有限公司 | 2018-10-23 | — | — | CN | claimed |
| CN-108699442-A | Liquid-crystal composition and liquid crystal display element | 捷恩智株式会社 | 2018-10-23 | — | — | CN | claimed |
| CN-108676004-A | A kind of four cyclics and its preparation method and application containing quinolinone | 中国海洋大学 | 2018-10-19 | — | — | CN | claimed |
| CN-108658975-A | A kind of nitrogenous compound and preparation method thereof and application as marine antifoulant | 中国海洋大学 | 2018-10-16 | — | — | CN | claimed |
| CN-108658986-A | A kind of four cyclics and purposes containing double lactams | 中国海洋大学 | 2018-10-16 | — | — | CN | claimed |
| CN-108658972-A | A kind of substituted lactams compounds and its preparation method and application | 中国海洋大学 | 2018-10-16 | — | — | CN | claimed |
| CN-108658985-A | A kind of alkaloid compound and application containing double lactams | 中国海洋大学 | 2018-10-16 | — | — | CN | claimed |
| CN-103930424-A | Compounds and compositions as c-kit kinase inhibitors | IRM LLC | 2014-07-16 | — | — | CN | claimed |
| CN-102558167-A | Thiazolidine derivant with GK and PPAR double excitation activity | INST MATERIA MEDICA CAMS | 2012-07-11 | — | — | CN | claimed |
| CN-102504229-A | Synthesis method of in-situ-enhanced thermosensitive polymer and degradable in-situ-enhanced injectable thermosensitive hydrogel | UNIV SUN YAT SEN | 2012-06-20 | — | — | CN | claimed |
| CN-100423356-C | Lithium-sulphur battery electrolyte and chargeable lithium-sulphur battery thereof | UNIV WUHAN (CN) | 2008-10-01 | — | — | CN | claimed |
| CN-101222950-A | Processes for production of 4-(biphenylyl)azetidin-2-one phosphonic acids | MICROBIA INC (US) | 2008-07-16 | — | — | CN | claimed |
| CN-1578660-A | Lactam-containing compounds and derivatives thereof as factor xa inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2005-02-09 | — | — | CN | claimed |
| CN-1242767-A | Fungicidal cyclic amides | DU PONT (US) | 2000-01-26 | — | — | CN | claimed |
| CN-1116850-A | Optically active beta-aminoalkoxyborane complexes | NISSAN CHEMICAL IND LTD (JP) | 1996-02-14 | — | — | CN | claimed |
| CN-1094728-A | Prepare the method for carbapeneme and penem and the new compound that relates to | SANKYO CO (JP) | 1994-11-09 | — | — | CN | claimed |
| CN-1022369-C | Heterocyclic-alkylene quinoxalinyloxyphenoxypropanoate herbicides | UNIROYAL CHEM CO INC (US) | 1993-10-13 | — | — | CN | claimed |