Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL647071 | 0.78 | GPR3 (0.35) | GPR3 | |
| Hydrochloric Acid SCHEMBL2860420 | 0.76 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL2865755 | 0.76 | GPR3 (0.30) | GPR3 | |
| Hydrochloric Acid SCHEMBL8511285 | 0.75 | BCHE (0.34) | — | |
| Hydrochloric Acid SCHEMBL9068686 | 0.75 | — | — | |
| Hydrochloric Acid SCHEMBL17972842 | 0.73 | SLC6A4 (0.30) | SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL7991740 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL2860647 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL6047523 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL2859423 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7618912-B2 | Preparation of supported catalyst systems | BASELL POLYOLEFINE GMBH (DE) | 2009-11-17 | — | — | US | claimed |
| US-20060166813-A1 | Preparation of supported catalyst systems | BASELL POLYOLEFINE GMBH (DE) | 2006-07-27 | — | — | US | claimed |
| EP-2513166-B1 | PROCESS FOR THE PREPARATION OF SUPPORTED CATALYSTS | BASELL POLYOLEFINE GMBH (DE) | 2017-04-05 | — | — | EP | disclosed |
| EP-1740626-B1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | BASELL POLYOLEFINE GMBH (DE) | 2014-10-22 | — | — | EP | disclosed |
| US-8859451-B2 | Process for the preparation of supported catalysts | BASELL POLYOLEFINE GMBH (DE) | 2014-10-14 | — | — | US | disclosed |
| US-8664140-B2 | Catalyst system for olefin polymerization, its production and use | BASELL POLYOLEFINE GMBH (DE) | 2014-03-04 | — | — | US | disclosed |
| US-20120283400-A1 | Process for the Preparation of Supported Catalysts | BASELL POLYOLEFINE GMBH (DE) | 2012-11-08 | — | — | US | disclosed |
| EP-2513166-A1 | PROCESS FOR THE PREPARATION OF SUPPORTED CATALYSTS | Basell Polyolefine GmbH (DE) | 2012-10-24 | — | — | EP | disclosed |
| EP-2173778-B1 | CATALYST SYSTEM FOR POLYMERIZATION OF OLEFINIC MONOMERS, PROCESS FOR PREPARING POLYMERS AND POLYMERS PREPARED BY THE PROCESS | BASELL POLYOLEFINE GMBH (DE) | 2012-04-18 | — | — | EP | disclosed |
| US-8133832-B2 | Catalyst system for polymerization of olefinic monomers, process for preparing polymers, and polymers prepared by the process | BASELL POLYOLEFINE GMBH (DE) | 2012-03-13 | — | — | US | disclosed |
| US-20110294969-A1 | Catalyst System for Olefin Polymerization, Its Production and Use | BASELL POLYOLEFINE GMBH (DE) | 2011-12-01 | — | — | US | disclosed |
| US-6127495-A | Preparation of polymers of C2 -C12 -alkenes with the addition of a reaction retarder | BASF AKTIENGESELLSCHAFT (DE) | 2000-10-03 | — | — | US | disclosed |
| US-6114478-A | IN STIRRED BED OF FINELY DIVIDED POLYMER FROM GAS PHASE KEPT IN MOTION BY MEANS OF STIRRER, THE TRANSITION METAL-CONTAINING CATALYST SOLID OF THE ZIEGLER-NATTA OR METALLOCENE CATALYST SYSTEM BEING FED TO REACTOR WITH C2-C8 ALK-1-ENE | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-05 | — | — | US | disclosed |
| US-6096845-A | Preparation of crystalline polymers by dispersion polymerization in the presence of metallocene catalyst systems | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | disclosed |
| US-5929185-A | OBTAINED BY POLYMERIZATION OF MONOMERS AT FROM-50 TO 300 DEGREES C. AND FROM 0.5 TO 3000 BAR IN THE PRESENCE OF A CATALYST SYSTEM WHICH CONTAINS, AS ACTIVE COMPONENTS, A METALLOCENE COMPLEX AND A COMPOUND FORMING METALLOCENIUM IONS | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-27 | — | — | US | disclosed |
| US-5908903-A | STERICALLY HINDERED ARYLOXYALUMINUM COMPOUND; ALUMOXANE | BASF AKTIENGESELLSCHAFT (DE) | 1999-06-01 | — | — | US | disclosed |
| US-5756607-A | CATALYSTS | BASF AKTIENGESELLSCHAFT (DE) | 1998-05-26 | — | — | US | disclosed |
| US-5688881-A | Oligomers and polymers of aminoalkenes | BASF AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| US-5639839-A | Oligomers and polymers of aminoalkenes | BASF AKTIENGESELLSCHAFT (DE) | 1997-06-17 | — | — | US | disclosed |
| US-5457171-A | Metallocene complex of metal of subgroup IV or V, alumoxane and cyclic boron compound | BASF AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |