SCHEMBL27268558

SCHEMBL27268558

CC(=O)NCC(=O)NCC(=O)NC(CO)C(C)=O

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 1/20 0.36
▸ TGFBR1 P36897 2/20 0.34
▸ MME P08473 2/20 0.33
▸ PSMB5 P28074 3/20 0.33
▸ POLB P06746 1/20 0.31
▸ PKM P14618 1/20 0.31
▸ GPR139 Q6DWJ6 2/20 0.31
▸ QRFPR Q96P65 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23589772 0.84 MME (0.34) F2TGFBR1MMEPSMB5
SCHEMBL865121 0.83 TGFBR1 (0.52) F2TGFBR1MMEKDM4E
SCHEMBL865120 0.83 TGFBR1 (0.52) F2TGFBR1MMEKDM4E
SCHEMBL19142250 0.81 F2 (0.38) F2PSMB5KDM4EMAPK1HIF1A
SCHEMBL25603596 0.79 TGFBR1 (0.37) TGFBR1MME
SCHEMBL1909473 0.75 MAPT (0.48) TGFBR1KDM4E
SCHEMBL15826905 0.75 MAPT (0.48) TGFBR1KDM4E
SCHEMBL13961927 0.74 CYP2C9 (0.45) TGFBR1MMEPSMB5POLB
SCHEMBL23080527 0.74 CYP2C9 (0.45) TGFBR1MMEPSMB5POLB
SCHEMBL16093456 0.74 FOLH1 (0.50) F2KDM4EMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024054870-A1 USE OF IL-7R-ALPHA-GAMMA AGONIST PEPTIDES IN CELL MANUFACTURING MEDIKINE, INC. (US) 2024-03-14 — — WO disclosed
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