Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.52 |
| ▸ | MME | P08473 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL865120 | 1.00 | TGFBR1 (0.52) | TGFBR1MMEKDM4EMAPTTHRB | |
| SCHEMBL27268558 | 0.83 | F2 (0.36) | TGFBR1MMEKDM4EF2 | |
| SCHEMBL27677170 | 0.83 | KDM4E (0.66) | TGFBR1MMEKDM4EMAPTTHRB | |
| SCHEMBL31016491 | 0.83 | CA2 (0.51) | MMEKDM4EMAPTTHRBALOX15 | |
| SCHEMBL468911 | 0.81 | ALDH1A1 (0.67) | MMEMAPTALDH1A1FOLH1NAALAD2 | |
| SCHEMBL468910 | 0.81 | ALDH1A1 (0.67) | MMEMAPTALDH1A1FOLH1NAALAD2 | |
| SCHEMBL6185155 | 0.81 | TGFBR1 (0.46) | TGFBR1MMEFNTAFNTBCA2 | |
| SCHEMBL12648688 | 0.80 | FOLH1 (0.59) | FOLH1FNTAFNTBNAALAD2NOD1 | |
| SCHEMBL468800 | 0.80 | FOLH1 (0.59) | FOLH1FNTAFNTBNAALAD2NOD1 | |
| SCHEMBL468801 | 0.80 | FOLH1 (0.59) | FOLH1FNTAFNTBNAALAD2NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160280737-A1 | ALKOXYSILANE DERIVATIVES OF N-ACYL AMINO ACIDS, N-ACYL DIPEPTIDES, AND N-ACYL TRIPEPTIDES, AND PARTICLES AND STABLE OIL-IN-WATER FORMULATIONS USING THE SAME | GELEST TECHNOLOGIES, INC. | 2016-09-29 | — | — | US | disclosed |
| US-9358200-B2 | Alkoxysilane derivatives of N-acyl amino acids, N-acyl dipeptides, and N-acyl tripeptides, and particles and stable oil-in-water formulations using the same | GELEST TECHNOLOGIES, INC. (US) | 2016-06-07 | — | — | US | disclosed |
| US-20120076840-A1 | Alkoxysilane Derivatives of N-Acyl Amino Acids, N-Acyl Dipeptides, and N-Acyl Tripeptides, and Particles and Stable Oil-in-Water Formulations Using the Same | GELEST TECHNOLOGIES, INC. (US) | 2012-03-29 | — | — | US | disclosed |
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280737-A1 | ALKOXYSILANE DERIVATIVES OF N-ACYL AMINO ACIDS, N-ACYL DIPEPTIDES, AND N-ACYL TRIPEPTIDES, AND PARTICLES AND STABLE OIL-IN-WATER FORMULATIONS USING THE SAME | ASNS, NPPA, AADAT | TGFBR1 3622/4885MME 1560/4885KDM4E 4287/4885 |
| US-20120076840-A1 | Alkoxysilane Derivatives of N-Acyl Amino Acids, N-Acyl Dipeptides, and N-Acyl Tripeptides, and Particles and Stable Oil-in-Water Formulations Using the Same | ASNS, NPPA, AADAT | TGFBR1 3622/4885MME 1560/4885KDM4E 4287/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.