Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 11/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 6/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27269749 | 0.92 | CYP2D6 (0.39) | CYP2D6TSHRUSP2CYP1A2HIF1A | |
| SCHEMBL22856411 | 0.87 | CYP2D6 (0.43) | CYP2D6TSHRUSP2CYP1A2HIF1A | |
| SCHEMBL25603399 | 0.85 | CYP2D6 (0.54) | CYP2D6TSHRUSP2CYP1A2HIF1A | |
| SCHEMBL23560350 | 0.82 | CYP2D6 (0.42) | CYP2D6TSHRUSP2CYP1A2HIF1A | |
| SCHEMBL24508736 | 0.82 | PIK3CD (0.46) | CYP2D6TSHRUSP2CYP1A2HIF1A | |
| SCHEMBL23945821 | 0.82 | EPHX2 (0.34) | CYP2D6TSHRUSP2CYP1A2HIF1A | |
| SCHEMBL23568464 | 0.80 | OPRM1 (0.41) | CYP2D6TSHRUSP2CYP1A2HIF1A | |
| SCHEMBL22790690 | 0.78 | CYP2D6 (0.41) | CYP2D6TSHRUSP2CYP1A2HIF1A | |
| SCHEMBL23945341 | 0.78 | CYP2D6 (0.36) | CYP2D6TSHRUSP2CYP1A2HIF1A | |
| SCHEMBL25833173 | 0.77 | USP2 (0.34) | CYP2D6TSHRUSP2CYP1A2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4393922-A1 | IRAK4 DEGRADATION AGENT, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Leadingtac Pharmaceutical Co. Ltd. (CN) | 2024-07-03 | — | — | EP | disclosed |