Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 10/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10538155 | 0.86 | KIF11 (0.46) | KCNN4CYP1A2NPSR1KMT2AHDAC3 | |
| SCHEMBL29934990 | 0.86 | KCNN4 (0.71) | KCNN4NPSR1KMT2AKCNE1KCNQ1 | |
| SCHEMBL409257 | 0.85 | KCNN4 (0.54) | KCNN4CYP1A2NPSR1MAPTKMT2A | |
| SCHEMBL10727252 | 0.85 | KCNN4 (0.48) | KCNN4CYP1A2NPSR1MAPTKMT2A | |
| SCHEMBL3523419 | 0.83 | KCNN4 (0.58) | KCNN4CYP1A2NPSR1MAPTKMT2A | |
| SCHEMBL45520 | 0.82 | CYP1A2 (0.56) | KCNN4CYP1A2NPSR1MAPTKMT2A | |
| SCHEMBL7880822 | 0.80 | CYP1A2 (0.54) | KCNN4CYP1A2NPSR1MAPTKMT2A | |
| SCHEMBL10909643 | 0.80 | CYP1A2 (0.54) | KCNN4CYP1A2NPSR1MAPTKMT2A | |
| SCHEMBL10403424 | 0.80 | CYP1A2 (0.54) | KCNN4CYP1A2NPSR1MAPTKMT2A | |
| SCHEMBL11522471 | 0.80 | CYP1A2 (0.54) | KCNN4CYP1A2NPSR1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029501-B2 | Method for making macrocycles | RIGEL PHARMACEUTICALS, INC. (US) | 2015-05-12 | — | — | US | claimed |
| US-20130217874-A1 | METHOD FOR MAKING MACROCYCLES | RIGEL PHARMACEUTICALS, INC. (US) | 2013-08-22 | — | — | US | claimed |
| WO-2012061408-A2 | METHOD FOR MAKING MACROCYCLES | RIGEL PHARMACEUTICALS. INC. (US) | 2012-05-10 | — | — | WO | claimed |
| CN-112680089-B | Long-acting antistatic coating and application and product thereof | 安徽辅朗光学材料有限公司 | 2022-07-05 | — | — | CN | disclosed |
| US-4039413-A | OXYGEN-FREE, UV OR VISIBLE LIGHT, ORGANIC PEROXIDE, ACRYLIC POLYMERSON | ROHM GMBH (DT) | 1977-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217874-A1 | METHOD FOR MAKING MACROCYCLES | EZR, SQLE, CBR3 | KCNN4 3004/4885CYP1A2 260/4885NPSR1 3208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.