SCHEMBL2727

SCHEMBL2727

O=C(O)/C=C\C=C/C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.67
TP53 P04637 1/20 0.67
EGLN1 Q9GZT9 1/20 0.67
EGLN3 Q9H6Z9 1/20 0.67
PPARA Q07869 1/20 0.42
GABRR1 P24046 2/20 0.42
GABRR2 P28476 2/20 0.42
BLM P54132 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
LMNA P02545 2/20 0.42
GABRR3 A8MPY1 1/20 0.42
APEX1 P27695 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ALOX15 P16050 1/20 0.41
RECQL P46063 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ACHE P22303 1/20 0.41
BACE1 P56817 1/20 0.41
MASP2 O00187 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL509417 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL30694696 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL30554051 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL2726 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL820982 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL351491 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
Hydrochloric Acid SCHEMBL10589654 0.96 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL17435363 0.96 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL17435366 0.96 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL2989833 0.96 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 28355 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260146112-A1 PHOTO-MELT-BULK POLYMERIZATION FOR RECYCLABLE POLYDIENE-DERIVATIVES PURDUE RESEARCH FOUNDATION (US) 2026-05-28 US claimed
CN-122007433-A Method for manufacturing silver-coated copper nanowires with core-shell structure using chemical reduction method 柏业公司 2026-05-12 CN claimed
EP-4499765-B1 COMPOSITIONS AND METHODS FOR TUNGSTEN ETCHING INHIBITION BASF SE (DE) 2026-05-06 EP claimed
WO-2026088166-A1 BIOSYNTHESIS OF PROTOCATECHUIC ACID VERB BIOTICS (US) 2026-04-30 WO claimed
US-20260117039-A1 UPCYCLING WASTE POLYSTYRENE TO ADIPIC ACID THROUGH A HYBRID CHEMICAL AND BIOLOGICAL PROCESS ALLIANCE FOR ENERGY INNOVATION LLC (US) 2026-04-30 US claimed
US-12606852-B2 Conversion of lignin-derived monomers to muconate by engineered pseudomonas Alliance for Energy Innovation, LLC (US) 2026-04-21 US claimed
US-12590050-B2 Preparation method of biobased adipic acid BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2026-03-31 US claimed
US-20260078078-A1 CONVERSION OF MUCONOLACTONE TO BETA-KETOADIPATES AND METHODS THEREFOR U.S. DEPARTMENT OF ENERGY 2026-03-19 US claimed
EP-4055074-B1 BIO-BASED RESIN FOR A COSMETIC COMPOSITION, AND PROCESS FOR THE PRODUCTION THEREOF ROQUETTE FRERES (FR) 2026-02-18 EP claimed
US-12551465-B2 Pharmaceutical composition for treatment of hypertrophic cardiomyopathy and treatment method using same composition CELLTRION INC. (KR) 2026-02-17 US claimed
US-4355107-A Production of muconic acid CELANESE CORPORATION (US) 1982-10-19 US claimed
US-4335010-A BY REACTING A COPPER HALIDE WITH OXYGEN AND AMMONIA OR AMMONIUM HYDROXIDE ALLIED CORPORATION (US) 1982-06-15 US claimed
US-4329498-A DECYCLIZATION, CYANATION, OXIDATION ALLIED CORPORATION (US) 1982-05-11 US claimed
US-4277419-A FROM PHENOLS, CATECHOLS, OR O-BENZOQUINONES ALLIED CHEMICAL CORPORATION (US) 1981-07-07 US claimed
EP-0022772-A1 HARDENABLE COMPOSITIONS SCED, Ian Robert (GB) 1981-01-28 EP claimed
EP-0009369-A1 Preparation of muconic acid mononitriles and copper(II)-ammonia reagent therefor ALLIED CORPORATION (US) 1980-04-02 EP claimed
WO-1980000409-A1 HARDENABLE COMPOSITIONS SCED I (GB) 1980-03-20 WO claimed
US-4101326-A Process for making stabilized polyesters used in radiation-sensitive compositions for lithographic plates having improved wear life including hindered phenols and phosphoric acid esters EASTMAN KODAK COMPANY (US) 1978-07-18 US claimed
US-4072734-A ACID OR NEUTRAL SALT OF 1,8-DIAZABICYCLO/5,4,0/UNDECENE-7 OSAKA SODA CO. LTD. (JA) 1978-02-07 US claimed
US-3952049-A EXO-TRIMETHYLENENORBORNYL, OILING AGENTS KAO SOAP CO., LTD. (JA) 1976-04-20 US claimed