SCHEMBL17435366

SCHEMBL17435366

O=C(O)/C=C\C=C/C(=O)O.[Fe]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
TP53 P04637 1/20 0.61
EGLN1 Q9GZT9 1/20 0.61
EGLN3 Q9H6Z9 1/20 0.61
PPARA Q07869 1/20 0.41
GABRR1 P24046 2/20 0.40
GABRR2 P28476 2/20 0.40
BLM P54132 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
LMNA P02545 2/20 0.40
GABRR3 A8MPY1 1/20 0.40
APEX1 P27695 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
ACHE P22303 1/20 0.39
BACE1 P56817 1/20 0.39
MASP2 O00187 1/20 0.39
F2 P00734 1/20 0.39
ALDH1A1 P00352 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17435363 1.00 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL509417 0.96 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL2727 0.96 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL351491 0.96 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL820982 0.96 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL2726 0.96 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL30554051 0.96 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL30694696 0.96 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL2989833 0.92 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA
Hydrochloric Acid SCHEMBL10589654 0.92 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026393-A1 EFFICIENT PRODUCTION OF CIS, CIS-MUCONIC ACID FROM MIXED SUBSTRATES OF GLUCOSE, D-XYLOSE AND L-ARABINOSE Alliance for Energy Innovation, LLC 2024-01-25 US disclosed
US-10337034-B2 Biomass conversion to fuels and chemicals ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2019-07-02 US disclosed
US-20180291405-A1 BIOMASS CONVERSION TO FUELS AND CHEMICALS Alliance for Energy Innovation, LLC 2018-10-11 US disclosed
US-10017792-B2 Biomass conversion to fuels and chemicals ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2018-07-10 US disclosed
CN-102481558-B Porous crystalline mixes solid as the purposes and equipment of catalyst for reduction of oxides of nitrogen 国立科学研究中心 2017-07-21 CN disclosed
US-20160017381-A1 BIOMASS CONVERSION TO FUELS AND CHEMICALS Alliance for Energy Innovation, LLC 2016-01-21 US disclosed
CN-102481558-A Use Of A Porous Crystalline Hybrid Solid As A Nitrogen Oxide Reduction Catalyst And Devices CT NAT RECH SCIENT FR 2012-05-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10017792-B2 Biomass conversion to fuels and chemicals ALG1, MGAM, ME1 TSHR 4723/4885TP53 1185/4885EGLN1 2488/4885
US-20180291405-A1 BIOMASS CONVERSION TO FUELS AND CHEMICALS ALG1, MGAM, ME1 TSHR 4723/4885TP53 1185/4885EGLN1 2488/4885
US-10337034-B2 Biomass conversion to fuels and chemicals ALG1, MGAM, ME1 TSHR 4723/4885TP53 1185/4885EGLN1 2488/4885
US-20240026393-A1 EFFICIENT PRODUCTION OF CIS, CIS-MUCONIC ACID FROM MIXED SUBSTRATES OF GLUCOSE, D-XYLOSE AND L-ARABINOSE UGDH, GPI, PGLS TSHR 2504/4885TP53 2074/4885EGLN1 3283/4885
US-20160017381-A1 BIOMASS CONVERSION TO FUELS AND CHEMICALS ALG1, MGAM, ME1 TSHR 4723/4885TP53 1185/4885EGLN1 2488/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.