SCHEMBL820982

SCHEMBL820982

O=C(O)/C=C\C=C\C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.67
TP53 P04637 1/20 0.67
EGLN1 Q9GZT9 1/20 0.67
EGLN3 Q9H6Z9 1/20 0.67
PPARA Q07869 1/20 0.42
GABRR1 P24046 2/20 0.42
GABRR2 P28476 2/20 0.42
BLM P54132 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
LMNA P02545 2/20 0.42
GABRR3 A8MPY1 1/20 0.42
APEX1 P27695 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 2/20 0.41
ALOX15 P16050 1/20 0.41
RECQL P46063 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ACHE P22303 1/20 0.41
BACE1 P56817 1/20 0.41
MASP2 O00187 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL509417 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL30694696 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL30554051 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL2727 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL2726 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL351491 1.00 TSHR (0.67) TSHRTP53EGLN1EGLN3PPARA
Hydrochloric Acid SCHEMBL10589654 0.96 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL17435363 0.96 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL17435366 0.96 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA
SCHEMBL2989833 0.96 TSHR (0.61) TSHRTP53EGLN1EGLN3PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12590050-B2 Preparation method of biobased adipic acid BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2026-03-31 US claimed
US-20250327097-A1 ORGANISMS PRODUCING LESS CROTONIC ACID GLOBAL BIOENERGIES (FR) 2025-10-23 US claimed
US-12344881-B2 Genetic engineering bacterium for de novo synthesis of cis,cis-muconic acid by taking glucose as substrate and applications thereof BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2025-07-01 US claimed
US-20250154091-A1 PREPARATION METHOD OF BIOBASED ADIPIC ACID BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2025-05-15 US claimed
WO-2025066218-A1 GENETICALLY ENGINEERED BACTERIUM FOR DE NOVO SYNTHESIS OF CIS,CIS-MUCONIC ACID BY USING GLUCOSE AS SUBSTRATE AND USE THEREOF 北京化工大学 2025-04-03 WO claimed
US-20250003152-A1 CITRIC ACID-CATALYSED CURRAN MODIFIED CARD BOARD MATERIALS CELLUCOMP LIMITED (GB) 2025-01-02 US claimed
US-20240327878-A1 PSEUDOMONAS PUTIDA STRAINS ENGINEERED FOR PRODUCTION OF MUCONIC ACID FROM P-METHOXYLATED BENZOIC ACIDS Alliance for Energy Innovation, LLC 2024-10-03 US claimed
US-20240327329-A1 AUTOXIDATION CATALYSIS FOR CARBON CARBON BOND CLEAVAGE IN LIGNIN Alliance for Energy Innovation, LLC 2024-10-03 US claimed
EP-4426890-A1 CITRIC ACID-CATALYSED CURRAN MODIFIED CARD BOARD MATERIALS Cellucomp Limited (GB) 2024-09-11 EP claimed
CN-113748168-B Layered high void fraction materials 普兰迪斯有限公司 2024-09-06 CN claimed
CN-118531035-A Construction method of three-bacterium artificial photosynthetic bacteria mixing system 天津大学 2024-08-23 CN claimed
CN-117980473-A Organisms producing less crotonic acid 环球生物能源公司 2024-05-03 CN claimed
CN-117529517-A Thermoset polymer foam and method of making same 普兰迪斯控股有限公司 2024-02-06 CN claimed
CN-117004547-B Genetically engineered bacterium for synthesizing cis, cis-muconic acid from glucose as substrate and application thereof 北京化工大学 2023-12-22 CN claimed
CN-117004547-A Genetically engineered bacterium for synthesizing cis, cis-muconic acid from glucose as substrate and application thereof 北京化工大学 2023-11-07 CN claimed
US-20230323410-A1 BACTERIAL CELLS AND METHODS FOR PRODUCTION OF 2-FLUORO-CIS,CIS-MUCONATE DANMARKS TEKNISKE UNIVERSITET (DK) 2023-10-12 US claimed
CN-116761841-A Method for producing non-planar articles 普兰迪斯控股有限公司 2023-09-15 CN claimed
WO-2023078904-A1 CITRIC ACID-CATALYSED CURRAN MODIFIED CARD BOARD MATERIALS CELLUCOMP LIMITED (GB) 2023-05-11 WO claimed
CN-113151204-B Catechol 1, 2-dioxygenase mutant and its use 南京工业大学 2022-04-15 CN claimed
US-20220056488-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF AROMATICS, 2,4-PENTADIENOATE AND 1,3-BUTADIENE GENOMATICA INC (US) 2022-02-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240327329-A1 AUTOXIDATION CATALYSIS FOR CARBON CARBON BOND CLEAVAGE IN LIGNIN CBR3, CBR1, POF1B TSHR 3865/4885TP53 2946/4885EGLN1 3219/4885
US-12590050-B2 Preparation method of biobased adipic acid ADIPOR1, ADIPOR2, MUC1 TSHR 3368/4885TP53 4009/4885EGLN1 3568/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.