SCHEMBL2727079

SCHEMBL2727079

COc1cc(F)c(-c2c3ccccc3c(-c3c(F)c(F)c(F)c(F)c3F)c3ccccc23)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.38
CYP1A2 P05177 4/20 0.36
CYP1A1 P04798 2/20 0.36
CYP1B1 Q16678 2/20 0.36
CA4 P22748 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 3/20 0.35
ALDH1A1 P00352 4/20 0.35
KDM4E B2RXH2 3/20 0.35
MEN1 O00255 2/20 0.35
HPGD P15428 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 2/20 0.35
EPAS1 Q99814 1/20 0.35
KDM1A O60341 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
GRM2 Q14416 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2712306 0.95 TAAR1 (0.35) TAAR1CYP1A2CYP1A1CYP1B1CA4
SCHEMBL2712308 0.93 TAAR1 (0.42) TAAR1CYP1A2CYP1A1CYP1B1CA4
SCHEMBL2712620 0.92 KDM4E (0.39) TAAR1CYP1A2CYP1A1CYP1B1CA4
SCHEMBL2725536 0.92 MAOA (0.35) TAAR1CYP1A2CYP1A1CYP1B1CA4
SCHEMBL2712953 0.91 TAAR1 (0.37) TAAR1CYP1A2CYP1A1CYP1B1CA4
SCHEMBL2712542 0.91 NQO2 (0.34) TAAR1MAPTEPAS1SMN1; SMN2NFE2L2
SCHEMBL2724680 0.90 MAOA (0.35) TAAR1CYP1A2CYP1A1CYP1B1CA4
SCHEMBL2709778 0.89 NFE2L2 (0.35) TAAR1CYP1A2CYP1A1CYP1B1L3MBTL1
SCHEMBL2724627 0.88 TAAR1 (0.37) TAAR1CYP1A2CYP1A1CYP1B1CA4
SCHEMBL2712038 0.88 CYP1A2 (0.37) TAAR1CYP1A2CYP1A1CYP1B1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 TAAR1 1993/4885CYP1A2 22/4885CYP1A1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.