Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | RBBP9 | O75884 | 5/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CASP3 | P42574 | 3/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL158422 | 0.96 | — | — | |
| Potassium SCHEMBL31461086 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL27718659 | 0.93 | — | — | |
| SCHEMBL31461088 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL28224778 | 0.93 | — | — | |
| Hydrochloric Acid SCHEMBL5013504 | 0.93 | ALDH1A1 (0.59) | ALDH1A1RBBP9PLA2G4ACES1KMT2A | |
| SCHEMBL31461084 | 0.93 | — | — | |
| Pyridine SCHEMBL5311951 | 0.92 | ALDH1A1 (0.50) | ALDH1A1RBBP9PLA2G4ACES1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28224779 | 0.91 | ALDH1A1 (0.57) | ALDH1A1RBBP9PLA2G4ACES1KMT2A | |
| SCHEMBL28029545 | 0.91 | ALDH1A1 (0.57) | ALDH1A1RBBP9PLA2G4ACES1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610188-B | Itrile group benzene thiazole carboxylic acid amides's compounds containing benzene carbon amidine structure, its preparation and purposes | 佛山市赛维斯医药科技有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-104610188-B | Itrile group benzene thiazole carboxylic acid amides's compounds containing benzene carbon amidine structure, its preparation and purposes | 佛山市赛维斯医药科技有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-104610188-B | Itrile group benzene thiazole carboxylic acid amides's compounds containing benzene carbon amidine structure, its preparation and purposes | 佛山市赛维斯医药科技有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-104628673-A | Nitrile benzene thiazolecarboxamide type compound containing tert-butylamidine structure and application thereof | FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-05-20 | — | — | CN | disclosed |
| CN-104610188-A | Nitrile benzene thiazolecarboxamide type compound containing phenyl amidine structure as well as preparation method and application thereof | FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-05-13 | — | — | CN | disclosed |
| CN-104592150-A | Cyclopropyl amidine structure containing cyanobenzene thiazolecarboxylic acid amide compound and application thereof | FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-05-06 | — | — | CN | disclosed |
| CN-1021010-C | SUBSTITUTED THIAZOLES COMPOSITION AND THEIR USE AS FUNGICIDES | MONSANTO CO (US) | 1993-06-02 | — | — | CN | disclosed |
| CN-1043127-A | Substituted thiazole and mycocide purposes thereof | MONSANTO CO (US) | 1990-06-20 | — | — | CN | disclosed |