SCHEMBL28029545

SCHEMBL28029545

NC(=O)C(N)=O.NC(=O)c1nccs1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.57
TSHR P16473 1/20 0.41
NOS1 P29475 1/20 0.41
HSD17B10 Q99714 1/20 0.41
RBBP9 O75884 5/20 0.41
PLA2G4A P47712 1/20 0.39
CASP3 P42574 3/20 0.39
SENP8 Q96LD8 3/20 0.39
SENP7 Q9BQF6 3/20 0.39
SENP6 Q9GZR1 3/20 0.39
MAPT P10636 2/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2D6 P10635 2/20 0.39
CYP2C19 P33261 2/20 0.39
CES1 P23141 1/20 0.38
FBP1 P09467 1/20 0.38
PDK1 Q15118 1/20 0.38
KMT2A Q03164 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL158422 0.96
SCHEMBL31461084 0.93
Potassium SCHEMBL31461086 0.93
Hydrochloric Acid SCHEMBL27718659 0.93
Hydrochloric Acid SCHEMBL5013504 0.93 ALDH1A1 (0.59) ALDH1A1TSHRNOS1HSD17B10RBBP9
SCHEMBL31461088 0.93
Ammonia Solution, Strong SCHEMBL28224778 0.93
Ammonia Solution, Strong SCHEMBL28224779 0.91 ALDH1A1 (0.57) ALDH1A1TSHRNOS1HSD17B10RBBP9
Benzene SCHEMBL27271103 0.91 ALDH1A1 (0.57) ALDH1A1TSHRNOS1HSD17B10RBBP9
Formic Acid SCHEMBL31678789 0.88 ALDH1A1 (0.53) ALDH1A1TSHRNOS1HSD17B10RBBP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107428694-A Antifungal pyrazoles 杜邦公司 2017-12-01 CN disclosed
CN-104884437-A Substituted tolyl fungicides DU PONT 2015-09-02 CN disclosed