Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 12/20 | 0.33 |
| ▸ | FABP5 | Q01469 | 12/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16945625 | 0.81 | CHRM2 (0.33) | CHRM2CRHR1HSD11B1 | |
| SCHEMBL19033003 | 0.80 | CHRM2 (0.33) | CHRM2CRHR1HSD11B1 | |
| SCHEMBL16945705 | 0.80 | CHRM2 (0.33) | CHRM2CRHR1HSD11B1 | |
| SCHEMBL22395062 | 0.76 | TSHR (0.37) | — | |
| SCHEMBL12258771 | 0.74 | HSD11B1 (0.36) | CHRM2FABP4FABP5CRHR1HSD11B1 | |
| SCHEMBL12888955 | 0.74 | CHRM2 (0.35) | CHRM2CRHR1HSD11B1 | |
| SCHEMBL23588266 | 0.71 | CHRM2 (0.36) | CHRM2FABP4FABP5HSD11B1CHRM4 | |
| SCHEMBL22629017 | 0.71 | KDM1A (0.43) | CHRM2FABP4FABP5HSD11B1CHRM4 | |
| SCHEMBL22395041 | 0.70 | CHRM2 (0.33) | CHRM2FABP4FABP5HSD11B1CHRM4 | |
| SCHEMBL23588192 | 0.70 | CHRM2 (0.33) | CHRM2FABP4FABP5HSD11B1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445909-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | Boehringer Ingelheim International GmbH (DE) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010141273-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-09 | — | — | WO | disclosed |