Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899126 | 0.81 | — | — | |
| SCHEMBL9482 | 0.79 | PARP15 (0.45) | PARP15PARP10TDP1RAB9ASLC6A3 | |
| SCHEMBL13851671 | 0.79 | FFAR1 (0.43) | PARP15PARP10TDP1RAB9ASLC6A3 | |
| SCHEMBL18381415 | 0.75 | CA1 (0.45) | PARP15PARP10LMNATSHR | |
| SCHEMBL2517712 | 0.74 | FFAR1 (0.49) | PARP15PARP10TDP1RAB9ASLC6A3 | |
| SCHEMBL2093337 | 0.74 | — | — | |
| SCHEMBL27629231 | 0.73 | PARP15 (0.46) | PARP15PARP10TDP1RAB9ASLC6A3 | |
| SCHEMBL2095928 | 0.71 | TBXAS1 (0.39) | PARP15PARP10TDP1RAB9ASLC6A3 | |
| SCHEMBL2095925 | 0.71 | SLC6A3 (0.37) | PARP15PARP10TDP1RAB9ASLC6A3 | |
| Oxalic Acid SCHEMBL1535383 | 0.70 | TAAR1 (0.66) | TDP1RAB9ANPC1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1019113-B | Process for preparing 3-arylhydrido-3-substituted propanamines | LILLY CO ELI (US) | 1992-11-18 | — | — | CN | disclosed |
| CN-87108175-A | The propylamine that 3-aryloxy-3-replaces | — | 1988-07-06 | — | — | CN | disclosed |