SCHEMBL2727273

SCHEMBL2727273

CCN(CC)[C](C)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50
ALDH1A1 P00352 3/20 0.47
MGLL Q99685 1/20 0.47
CHRM2 P08172 1/20 0.44
HTR1A P08908 1/20 0.44
ADRA2A P08913 1/20 0.44
CHRM1 P11229 1/20 0.44
DRD1 P21728 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
ADRA1A P35348 1/20 0.44
OPRM1 P35372 1/20 0.44
DRD3 P35462 1/20 0.44
SLC6A3 Q01959 1/20 0.44
KCNH2 Q12809 1/20 0.44
CES1 P23141 2/20 0.43
CES2 O00748 1/20 0.43
AKR1B1 P15121 1/20 0.43
TP53 P04637 1/20 0.42
TSHR P16473 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8061232 0.81 LMNA (0.48) LMNAALDH1A1MGLLCHRM2HTR1A
SCHEMBL195224 0.77 LMNA (0.58) LMNAALDH1A1CES1CES2AKR1B1
SCHEMBL28816150 0.75 CYP2A6 (0.52) ALDH1A1TSHR
SCHEMBL8279944 0.72 LMNA (0.63) LMNAALDH1A1MGLLTSHRMAPK1
SCHEMBL2424438 0.72 ALDH1A1 (0.46) LMNAALDH1A1MGLLCHRM2HTR1A
SCHEMBL3456186 0.72 LMNA (0.68) LMNAALDH1A1MGLLTSHRMAPK1
Benzene SCHEMBL9806260 0.72 CES1 (0.50) ALDH1A1CES1CES2AKR1B1TP53
SCHEMBL531194 0.72 CES1 (0.50) ALDH1A1CES1CES2AKR1B1TP53
SCHEMBL11339635 0.72 CES1 (0.50) ALDH1A1CES1CES2AKR1B1TP53
SCHEMBL3631071 0.71 POLB (0.60) LMNAALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2632944-B1 METHOD FOR PURIFYING HUMAN GRANULOCYTE-COLONY STIMULATING FACTOR FROM RECOMBINANT E. COLI HANMI SCIENCE CO LTD (KR) 2017-06-21 EP disclosed
US-9193761-B2 Method for purifying human granulocyte-colony stimulating factor from recombinant E. coli HANMI SCIENCE CO., LTD (KR) 2015-11-24 US disclosed
US-8563650-B2 Method for producing resin dispersions and resin particles SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2013-10-22 US disclosed
EP-2632944-A2 METHOD FOR PURIFYING HUMAN GRANULOCYTE-COLONY STIMULATING FACTOR FROM RECOMBINANT E. COLI Hanmi Science Co., Ltd. (KR) 2013-09-04 EP disclosed
US-20130211054-A1 METHOD FOR PURIFYING HUMAN GRANULOCYTE-COLONY STIMULATING FACTOR FROM RECOMBINANT E. COLI HANMI SCIENCE CO., LTD. (KR) 2013-08-15 US disclosed
WO-2012057529-A2 METHOD FOR PURIFYING HUMAN GRANULOCYTE-COLONY STIMULATING FACTOR FROM RECOMBINANT E. COLI HANMI HOLDINGS CO., LTD. (KR) 2012-05-03 WO disclosed
US-20090280423-A1 METHOD FOR PRODUCING RESIN DISPERSIONS AND RESIN PARTICLES SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2009-11-12 US disclosed
US-20070264710-A1 Process for Purifying Human Thrombopoietin with High Content of Sialic Acid DAEWOONG CO., LTD. (KR) 2007-11-15 US disclosed
EP-1670821-A4 PROCESS FOR PURIFYING HUMAN THROMBOPOIETIN WITH HIGH CONTENT OF SIALIC ACID DAEWOONG CO LTD (KR) 2006-11-29 EP disclosed
EP-1670821-A1 PROCESS FOR PURIFYING HUMAN THROMBOPOIETIN WITH HIGH CONTENT OF SIALIC ACID Daewoong Co., Ltd. (KR) 2006-06-21 EP disclosed
WO-2005033135-A1 PROCESS FOR PURIFYING HUMAN THROMBOPOIETIN WITH HIGH CONTENT OF SIALIC ACID DAEWOONG CO., LTD. (KR) 2005-04-14 WO disclosed
US-4913793-A MIXTURE OF ANIONIC, CATIONIC EXCHANGE POLYMERS BROADLEY-JAMES CORPORATION (US) 1990-04-03 US disclosed
WO-1989003045-A1 PROTEIN ASSAY DEVICE AND METHOD CAMBRIDGE LIFE SCIENCES PLC (GB) 1989-04-06 WO disclosed
EP-0310314-A1 Protein assay device and method CAMBRIDGE LIFE SCIENCES PLC (GB) 1989-04-05 EP disclosed
EP-0215614-A2 Reference electrode BROADLEY-JAMES CORPORATION (US) 1987-03-25 EP disclosed