Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.63 |
| ▸ | CPT1A | P50416 | 1/20 | 0.48 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SNCA | P37840 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.46 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8528458 | 0.92 | GPR84 (0.73) | GPR84CPT1ACPT1BNPC1SNCA | |
| SCHEMBL8427130 | 0.88 | GPR84 (0.67) | GPR84CPT1ACPT1BNPC1IDO1 | |
| SCHEMBL8951231 | 0.87 | GPR84 (0.63) | GPR84CPT1ACPT1BNPC1SNCA | |
| SCHEMBL29251314 | 0.85 | GPR84 (0.78) | GPR84NPC1MAPTMEN1KMT2A | |
| SCHEMBL9373490 | 0.85 | GPR84 (0.60) | GPR84CPT1ACPT1BNPC1SNCA | |
| SCHEMBL9373131 | 0.84 | GPR84 (0.59) | GPR84CPT1ACPT1BNPC1SNCA | |
| SCHEMBL8530246 | 0.83 | GPR84 (0.65) | GPR84CPT1ACPT1BSNCAIDO1 | |
| SCHEMBL3676424 | 0.83 | GPR84 (0.58) | GPR84NPC1GABRA1GABRB2MAPT | |
| SCHEMBL29871648 | 0.83 | GPR84 (0.87) | GPR84NPC1HTR1AHTR1DHTR1B | |
| SCHEMBL10644891 | 0.82 | GPR84 (0.48) | GPR84CPT1ACPT1BNPC1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1017425-B | Process for preparing heterocyclic amide derivatives | ICI AMERICA INC (US) | 1992-07-15 | — | — | CN | disclosed |