Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.40 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | IL1B | P01584 | 1/20 | 0.38 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26064740 | 0.92 | CRBN (0.41) | CRBNMAP1LC3BDDB1STAT3IKZF3 | |
| SCHEMBL30733869 | 0.89 | HDAC1 (0.41) | CRBNMAP1LC3BDDB1STAT3IKZF3 | |
| SCHEMBL19453082 | 0.88 | HDAC3 (0.41) | CRBNMAP1LC3BDDB1STAT3IKZF3 | |
| SCHEMBL21554525 | 0.88 | CRBN (0.42) | CRBNMAP1LC3BDDB1IKZF3BRD4 | |
| SCHEMBL19503975 | 0.82 | CRBN (0.54) | CRBNDDB1IKZF3BRD4TNF | |
| SCHEMBL25905193 | 0.81 | MAP1LC3B (0.48) | CRBNMAP1LC3BDDB1STAT3CA2 | |
| SCHEMBL19453081 | 0.81 | CRBN (0.41) | CRBNMAP1LC3BDDB1STAT3BRD4 | |
| SCHEMBL19451425 | 0.81 | CRBN (0.37) | CRBNMAP1LC3BDDB1STAT3IKZF3 | |
| SCHEMBL19541981 | 0.80 | CRBN (0.43) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL24480802 | 0.80 | CRBN (0.47) | CRBNDDB1IKZF3BRD4TNF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240217988-A1 | ESTROGEN RECEPTOR ANTAGONIST | SHENZHEN FORWARD PHARMACEUTICALS CO., LIMITED (CN) | 2024-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217988-A1 | ESTROGEN RECEPTOR ANTAGONIST | GPER1, ESR1, ESR2 | CRBN 2823/4885MAP1LC3B 1346/4885DDB1 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.