Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RRM1 | P23921 | 1/20 | 0.50 |
| ▸ | GLP1R | P43220 | 8/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 4/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | EPOR | P19235 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20146951 | 0.88 | GLP1R (0.52) | RRM1GLP1RDPP7GNAI3GNAO1 | |
| SCHEMBL17922789 | 0.88 | GLP1R (0.54) | GLP1RDPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL16493177 | 0.87 | GLP1R (0.53) | GLP1RDPP7GNAI3GNAO1GNAI1 | |
| SCHEMBL16638308 | 0.86 | GLP1R (0.59) | RRM1GLP1RDPP7GNAI3GNAO1 | |
| SCHEMBL18551937 | 0.85 | GLP1R (0.64) | RRM1GLP1RDPP7GNAI3GNAO1 | |
| SCHEMBL26903901 | 0.84 | GLP1R (0.50) | RRM1GLP1RTLR2EPORITGB3 | |
| SCHEMBL27292709 | 0.83 | GLP1R (0.49) | GLP1RITGB3ITGA2B | |
| SCHEMBL16382930 | 0.82 | GLP1R (0.58) | GLP1RGNAI3GNAO1GNAI1TLR2 | |
| SCHEMBL19034928 | 0.82 | GLP1R (0.55) | GLP1REPORITGB3ITGA2B | |
| SCHEMBL19049678 | 0.82 | GLP1R (0.55) | GLP1REPORITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024059472-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-03-21 | — | — | WO | disclosed |