Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705156 | 0.76 | ALDH1A1 (0.44) | F12ALDH1A1POLBKDM4EBRD4 | |
| SCHEMBL13997455 | 0.71 | KCNH2 (0.41) | F12ALDH1A1ACKR3PRMT5WDR77 | |
| SCHEMBL1520745 | 0.69 | EGFR (0.42) | ALDH1A1CYP2C19ACKR3PRMT5WDR77 | |
| SCHEMBL27862075 | 0.69 | ALDH1A1 (0.46) | F12ALDH1A1MAPTHPGDACKR3 | |
| SCHEMBL13871920 | 0.68 | CES2 (0.40) | ALDH1A1KDM4EMEN1MAPTHPGD | |
| SCHEMBL3749720 | 0.67 | ALDH1A1 (0.57) | ALDH1A1MAPTPRMT5WDR77F2 | |
| SCHEMBL5800011 | 0.67 | ALDH1A1 (0.57) | ALDH1A1MAPTPRMT5WDR77F2 | |
| SCHEMBL3026559 | 0.67 | CYP2C9 (0.67) | ALDH1A1POLBMEN1LMNACYP2C9 | |
| SCHEMBL27362318 | 0.67 | KCNH2 (0.42) | F12ALDH1A1HPGDACKR3PRMT5 | |
| SCHEMBL859610 | 0.66 | KCNH2 (0.44) | F12ALDH1A1ACKR3PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1017707-B | PROCESS FOR PREPARATION OF NEW THIAZOLE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 1992-08-05 | — | — | CN | disclosed |
| CN-86108205-A | New thiazolium compounds and preparation method thereof and their pharmaceutical composition | — | 1987-06-17 | — | — | CN | disclosed |