SCHEMBL27278

SCHEMBL27278

C=C(C)C(=O)OCC(C)(C)CO

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
THRB P10828 1/20 0.42
ALDH1A1 P00352 3/20 0.40
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
SERPINE1 P05121 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL18037940 0.94 TSHR (0.41) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL19433445 0.94 TSHR (0.41) TSHRTHRBALDH1A1
SCHEMBL3733736 0.94 TSHR (0.44) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL15326991 0.93 TSHR (0.40) TSHRTHRBALDH1A1TP53CYP3A4
SCHEMBL25783228 0.93 THRB (0.42) TSHRTHRBALDH1A1SERPINE1
1,5-Pentanediol SCHEMBL944486 0.91 TSHR (0.43) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL472433 0.89 TSHR (0.38) TSHRTHRBALDH1A1
SCHEMBL36263 0.89 TSHR (0.38) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL15337 0.89 TSHR (0.50) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL3163719 0.88 TSHR (0.37) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 23359 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569639-B1 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE (US) 2025-09-24 EP claimed
EP-2794723-B2 SILICONE HYDROGELS HAVING A STRUCTURE FORMED VIA CONTROLLED REACTION KINETICS JOHNSON & JOHNSON VISION CARE (US) 2025-06-04 EP claimed
WO-2025059244-A2 UV CURABLE COATINGS SYSTEM FOR IMPROVED SCRATCH RESISTANCE SWIMC LLC (US) 2025-03-20 WO claimed
US-20250084273-A1 UV CURABLE COATINGS SYSTEM FOR IMPROVED SCRATCH RESISTANCE SWIMC LLC 2025-03-13 US claimed
CN-118388706-A Sand-carrying drag reducer for shale oil fracturing and water-dispersible polymerization method thereof 大庆高新区华龙祥化工有限公司 2024-07-26 CN claimed
US-12017480-B2 Tire having a composition comprising an ethylene-rich elastomer, a peroxide and a specific acrylate derivative COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2024-06-25 US claimed
EP-3810064-B1 THERMOACTIVE DENTAL COMPOSITE COMPOSITION VOCO GMBH (DE) 2024-05-29 EP claimed
US-20240157322-A1 CROSSLINKED CORE-SHELL MICROCAPSULES FIRMENICH SA (CH) 2024-05-16 US claimed
US-20240150592-A1 PHOTOCURABLE CONDUCTIVE BLACK COMPOSITION AND A METHOD FOR FORMING A CURED PRODUCT THEREOF U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-05-09 US claimed
US-11965115-B2 Anti-corrosion coating composition GLOBAL GRAPHENE GROUP, INC. (US) 2024-04-23 US claimed
EP-0409623-A1 Adhesive composition SOMAR CORPORATION (JP) 1991-01-23 EP claimed
EP-0386777-A2 PS plate for use in making lithographic printing plate requiring no dampening water Fuji Photo Film Co., Ltd. (JP) 1990-09-12 EP claimed
EP-0177791-B1 RADIATION CURABLE PRIMER COATING COMPOSITIONS SUMITOMO METAL INDUSTRIES, LTD. (JP) 1990-08-16 EP claimed
US-4777191-A TETRAPEROXY ESTERS OF BENZOPHENONE NIPPON OIL & FATS CO., LTD. (JP) 1988-10-11 US claimed
EP-0240752-A1 Erasable optical disk having an improved optically transparent substrate MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1987-10-14 EP claimed
US-4698174-A ACRYLIC POLYMER AND NITRILOTRIACETIC ACID AND/OR ITS SALTS IMPROVE HANDLING PROPERTIES BASF AKTIENGESELLSCHAFT (DE) 1987-10-06 US claimed
EP-0078548-B1 SILICIC ACID HETEROPOLYCONDENSATES AND THEIR USE IN OPTICAL LENSES, ESPECIALLY CONTACT LENSES FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1987-01-21 EP claimed
US-4511645-A ALLYL METHACRYLATE-METHACRYLIC ACID COPOLYMER, CURING AGENT, PHOTOINITIATOR FUJI PHOTO FILM CO., LTD. (JP) 1985-04-16 US claimed
US-4447328-A Filler for liquid chromatography and method for separating water-soluble substances using said filler Sekisu Kagaku Kogyo Kabushiki Kaisha (JP) 1984-05-08 US claimed
US-4396706-A ADDITION INTERPOLYMER PARTICLES, MATTES FUJI PHOTO FILM CO., LTD. (JP) 1983-08-02 US claimed