Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27278 | 0.94 | TSHR (0.45) | TSHRTHRBALDH1A1SERPINE1POLB | |
| SCHEMBL15337 | 0.92 | TSHR (0.50) | TSHRTHRBALDH1A1SERPINE1POLB | |
| SCHEMBL25783228 | 0.91 | THRB (0.42) | TSHRTHRBALDH1A1SERPINE1 | |
| Methacrylic Acid SCHEMBL18037940 | 0.89 | TSHR (0.41) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL19433445 | 0.89 | TSHR (0.41) | TSHRTHRBALDH1A1 | |
| SCHEMBL15326991 | 0.87 | TSHR (0.40) | TSHRTHRBALDH1A1TP53CYP3A4 | |
| SCHEMBL9576258 | 0.86 | THRB (0.47) | TSHRTHRBALDH1A1SERPINE1POLB | |
| Methacrylic Acid SCHEMBL28241961 | 0.86 | TSHR (0.45) | TSHRTHRBALDH1A1SERPINE1POLB | |
| SCHEMBL9640205 | 0.86 | THRB (0.57) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11682314 | 0.86 | TSHR (0.45) | TSHRTHRBALDH1A1SERPINE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106661255-A | Conductive multilayer sheet for thermal forming applications | 沙特基础工业全球技术有限公司 | 2017-05-10 | — | — | CN | disclosed |
| US-7828432-B2 | Hybrid contact lenses prepared with expansion controlled polymeric materials | SYNERGEYES, INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-20080291391-A1 | HYBRID CONTACT LENSES PREPARED WITH EXPANSION CONTROLLED POLYMERIC MATERIALS | SYNERGEYES, INC. | 2008-11-27 | — | — | US | disclosed |