Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27318232 | 0.86 | MAPK1 (0.61) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL1021195 | 0.85 | MAPK1 (0.66) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL11550363 | 0.82 | MAPK1 (0.61) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL10999891 | 0.82 | MAPK1 (0.61) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL28941324 | 0.82 | P2RY6 (0.41) | MAPK1TDP1CYP3A4PNMTGABRA1 | |
| SCHEMBL27721621 | 0.79 | MAPK1 (0.43) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL7757448 | 0.78 | TDP1 (0.56) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL10763639 | 0.78 | MAPK1 (0.56) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL58874 | 0.77 | MAPK1 (1.00) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL29376406 | 0.77 | MAPK1 (1.00) | MAPK1TDP1CYP3A4TSHRTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102618205-B | Polyurethane composite adhesive | SUZHOU SIDIKE NEW MATERIAL SCIENCE AND TECHNOLOGY CORP | 2013-10-30 | — | — | CN | claimed |
| CN-103304446-A | Derivatization method of optically active phenylacetylene compound | UNIV HARBIN ENG | 2013-09-18 | — | — | CN | claimed |
| CN-102911634-A | Loudspeaker center adhesive and preparation method thereof | SUZHOU ADHESIVES FACTORY CO LTD | 2013-02-06 | — | — | CN | claimed |
| CN-102898611-A | Preparation method for organic silicon polyurethane adhesive | SUZHOU ADHESIVES FACTORY CO LTD | 2013-01-30 | — | — | CN | claimed |
| CN-102618205-A | Polyurethane composite adhesive | SUZHOU SIDIKE NEW MATERIAL SCIENCE AND TECHNOLOGY CORP | 2012-08-01 | — | — | CN | claimed |
| CN-101356165-A | Process for preparing gemcitabine and related intermediates | CHEMAGIS LTD (IL) | 2009-01-28 | — | — | CN | claimed |
| CN-103382197-A | N-methylaminomethyl isoindole compounds and compositions comprising and methods of using the same | CELGENE CORP | 2013-11-06 | — | — | CN | disclosed |
| CN-102618205-B | Polyurethane composite adhesive | SUZHOU SIDIKE NEW MATERIAL SCIENCE AND TECHNOLOGY CORP | 2013-10-30 | — | — | CN | disclosed |
| CN-103304446-A | Derivatization method of optically active phenylacetylene compound | UNIV HARBIN ENG | 2013-09-18 | — | — | CN | disclosed |
| CN-103026223-A | Separating agent for optical isomers | DAICEL CORP | 2013-04-03 | — | — | CN | disclosed |
| CN-102911634-A | Loudspeaker center adhesive and preparation method thereof | SUZHOU ADHESIVES FACTORY CO LTD | 2013-02-06 | — | — | CN | disclosed |
| CN-102898611-A | Preparation method for organic silicon polyurethane adhesive | SUZHOU ADHESIVES FACTORY CO LTD | 2013-01-30 | — | — | CN | disclosed |
| CN-102898416-A | 5-substituted quinazolinone derivatives as anti-cancer agents | CELGENE CORP | 2013-01-30 | — | — | CN | disclosed |
| CN-101356165-A | Process for preparing gemcitabine and related intermediates | CHEMAGIS LTD (IL) | 2009-01-28 | — | — | CN | disclosed |
| CN-101115528-A | Inhibitors of HIV-1 capsid formation: substituted aryl aminomethyl thiazole ureas and analogs thereof | ACHILLION PHARMACEUTICALS INC (US) | 2008-01-30 | — | — | CN | disclosed |
| CN-1241916-C | Novel acardite compound, its preparation method and medicinal composition containing said compound | SERVIER LAB (FR) | 2006-02-15 | — | — | CN | disclosed |
| CN-1549714-A | Aminoisoxazole derivatives active as kinase inhibitors | — | 2004-11-24 | — | — | CN | disclosed |
| CN-1337395-A | Novel acardite compound, its preparation method and medicinal composition containing said compound | SERVIER LAB (FR) | 2002-02-27 | — | — | CN | disclosed |
| CN-1017996-B | IMINOOXAZOLIDINE HERBICIDE COMPOSITION | STAUFFER CHEMICAL CO (US) | 1992-08-26 | — | — | CN | disclosed |
| CN-87107006-A | Imino- azoles alkane and preparation method and using method | — | 1988-06-29 | — | — | CN | disclosed |