SCHEMBL27318232

SCHEMBL27318232

NCc1cc(N=C=O)ccc1Cl

nearest known ligand 0.61

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
CYP3A4 P08684 2/20 0.41
TSHR P16473 1/20 0.41
TRPA1 O75762 1/20 0.41
PNMT P11086 2/20 0.39
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
CYP1A2 P05177 1/20 0.35
HTR3E A5X5Y0 1/20 0.32
HTR3B O95264 1/20 0.32
HTR3A P46098 1/20 0.32
HTR3D Q70Z44 1/20 0.32
HTR3C Q8WXA8 1/20 0.32
DPP4 P27487 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27280280 0.86 MAPK1 (0.61) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL11552139 0.85 MAPK1 (0.66) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL281996 0.84 MAPK1 (0.63) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL31182116 0.82 MAPK1 (0.61) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL1122281 0.82 MAPK1 (0.61) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL27515771 0.79 MAPK1 (0.43) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL27721584 0.79 MAPK1 (0.43) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL27285550 0.77 MAPK1 (0.42) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL58874 0.77 MAPK1 (1.00) MAPK1TDP1CYP3A4TSHRTRPA1
SCHEMBL29376406 0.77 MAPK1 (1.00) MAPK1TDP1CYP3A4TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1050124-C Herbicide containing oxazolidinedione derivatives SAGAMI CHEM RES (JP) 2000-03-08 CN disclosed
CN-1027069-C Process for producing oxazolidinedione derivative SAGAMI CHEM RES (JP) 1994-12-21 CN disclosed
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed
CN-86108416-A Oxazolidinedione derivative, process for producing the same, and herbicide containing the same 1987-07-29 CN disclosed