Cyclohexane

Cyclohexane

SCHEMBL27280449

C1CCCCC1.N.NC(=O)N(N)N

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 4/20 0.37
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
OR51E2 Q9H255 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
EPHX1 P07099 1/20 0.32
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopropane SCHEMBL28079209 1.00 ALOX5 (0.37) ALOX5ALDH1A1LMNAOR51E2TDP1
Cyclopentane SCHEMBL28068666 0.96 ALOX5 (0.39) ALOX5ALDH1A1LMNAOR51E2TDP1
Cyclohexane SCHEMBL27505705 0.96 ALOX5 (0.39) ALOX5ALDH1A1LMNAOR51E2TDP1
Ammonia Solution, Strong SCHEMBL27734425 0.89
SCHEMBL2917853 0.84
Hydrochloric Acid SCHEMBL28035645 0.81
SCHEMBL28126805 0.81
Methane SCHEMBL27588159 0.81
SCHEMBL28161511 0.80 ALOX5 (0.45) ALOX5ALDH1A1EPHX1
Hydrochloric Acid SCHEMBL27661442 0.77 LMNA (0.39) ALDH1A1LMNAOR51E2TDP1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101325955-A Methods of treating cancer with SAHA and pemetrexed MERCK & CO INC (US) 2008-12-17 CN disclosed
CN-1014606-B CONTINUOUS PREPARATION METHOD OF MONOISOCYANATE OR POLYISOCYANATE BEYER GMBH (DE) 1991-11-06 CN disclosed
CN-1034536-A The continuous preparation method of monoisocyanates or polyisocyanates BAYER AG (DE) 1989-08-09 CN disclosed