Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4371193 | 0.83 | ZDHHC20 (0.38) | TSHRALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL8983818 | 0.77 | TSHR (0.33) | TSHRALDH1A1 | |
| SCHEMBL5489834 | 0.72 | TSHR (0.43) | TSHRALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL13862580 | 0.72 | TSHR (0.53) | TSHRALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL429457 | 0.70 | TSHR (0.42) | TSHRALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL2727312 | 0.69 | ZDHHC20 (0.42) | TSHRALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL26497601 | 0.68 | ZDHHC20 (0.40) | TSHRALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL26496068 | 0.68 | ZDHHC20 (0.40) | TSHRALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL4732343 | 0.68 | TSHR (0.41) | TSHRALDH1A1ZDHHC20ZDHHC2 | |
| SCHEMBL157071 | 0.67 | TSHR (0.39) | TSHRALDH1A1ZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3558212-A1 | DIRECT DENTAL FILLING COMPOSITION | Dentsply DeTrey GmbH (DE) | 2019-10-30 | — | — | EP | disclosed |
| WO-2019173656-A1 | DENTAL COMPOSITION | DENTSPLY SIRONA INC. (US) | 2019-09-12 | — | — | WO | disclosed |
| WO-2019072787-A1 | PHOTOCURABLE DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2019-04-18 | — | — | WO | disclosed |
| WO-2018114540-A1 | DIRECT DENTAL FILLING COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2018-06-28 | — | — | WO | disclosed |
| EP-3307229-A1 | AQUEOUS DENTAL GLASS IONOMER COMPOSITION | Dentsply DeTrey GmbH (DE) | 2018-04-18 | — | — | EP | disclosed |
| EP-3277248-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2018-02-07 | — | — | EP | disclosed |
| WO-2017042333-A1 | POLYMERIZABLE POLYACIDIC POLYMER | DENTSPLY DETREY GMBH (DE) | 2017-03-16 | — | — | WO | disclosed |
| WO-2016202744-A1 | AQUEOUS DENTAL GLASS IONOMER COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2016-12-22 | — | — | WO | disclosed |
| WO-2016156363-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2016-10-06 | — | — | WO | disclosed |
| EP-3068363-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015067815-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2015-05-14 | — | — | WO | disclosed |
| WO-2014114446-A1 | POLYMERIZABLE DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2014-07-31 | — | — | WO | disclosed |
| EP-2655427-A1 | POLYMER FOR A GLASS IONOMER CEMENT | Dentsply DeTrey GmbH (DE) | 2013-10-30 | — | — | EP | disclosed |
| EP-2629741-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2013-08-28 | — | — | EP | disclosed |
| EP-2629740-A1 | DENTAL COMPOSITION | Dentsply DeTrey GmbH (DE) | 2013-08-28 | — | — | EP | disclosed |
| WO-2012119793-A2 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012084206-A1 | POLYMER FOR A GLASS IONOMER CEMENT | DENTSPLY DETREY GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012052163-A1 | DENTAL CEMENT COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012052160-A1 | DENTAL COMPOSITION | DENTSPLY DETREY GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012052161-A1 | DENTAL COMPOSITION | DENTSPLY DE TREY GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |