Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB2 | Q9UBS0 | 2/20 | 0.44 |
| ▸ | PGK1 | P00558 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.39 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL577465 | 0.71 | NPC1 (0.42) | RPS6KB2NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL27691177 | 0.71 | PGK1 (0.46) | RPS6KB2PGK1NPC1ALDH1A1KDM4E | |
| SCHEMBL3941444 | 0.70 | MEN1 (0.42) | RPS6KB2NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL27289634 | 0.68 | ADORA2A (0.37) | NPC1ALDH1A1KDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL732915 | 0.68 | RPS6KB2 (0.49) | RPS6KB2NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL2780877 | 0.68 | RPS6KB2 (0.56) | RPS6KB2NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL10854744 | 0.67 | ALDH1A1 (0.41) | RPS6KB2NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL1637752 | 0.67 | GAA (0.43) | PGK1NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL6273269 | 0.67 | ALDH1A1 (0.51) | RPS6KB2NPC1ALDH1A1KDM4ERAB9A | |
| SCHEMBL24172961 | 0.66 | NPC1 (0.46) | RPS6KB2NPC1ALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1009197-B | Process for preparing N, 3-disubstituted 2-oxindole-1-carboxamides | PFIZER (US) | 1990-08-15 | — | — | CN | disclosed |