⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27288685 | 0.78 | PDE7A (0.32) | — | |
| SCHEMBL1709256 | 0.72 | — | — | |
| SCHEMBL3198922 | 0.70 | — | — | |
| SCHEMBL9382652 | 0.69 | CES1 (0.40) | — | |
| SCHEMBL9410349 | 0.67 | — | — | |
| SCHEMBL7469392 | 0.67 | — | — | |
| SCHEMBL1277173 | 0.65 | — | — | |
| SCHEMBL266174 | 0.65 | — | — | |
| SCHEMBL4550191 | 0.65 | — | — | |
| SCHEMBL1083648 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1009553-B | PREPARATION METHOD OF COMPOUNDS OF 5,6-DIHYDRO-4H-CYOCLOPENTADIENE (B) THIOPHENE-6-CARBOXYLIC ACID | LYON INDUSTRAL MEDICINE CO (FR) | 1990-09-12 | — | — | CN | disclosed |
| CN-85106178-A | 5,6 dihydros-4H-cyclopenta (b) thiophene-6-carboxylic acid compound and contain the preparation method of the medicine of these compounds | — | 1987-03-04 | — | — | CN | disclosed |