Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11421425 | 0.71 | GABRA1 (0.40) | PDE7AALDH1A1SMN1; SMN2 | |
| SCHEMBL956562 | 0.71 | ALDH1A1 (0.43) | LMNANPC1ALDH1A1RAB9A | |
| SCHEMBL23877337 | 0.69 | KEAP1 (0.31) | PDE7A | |
| SCHEMBL22863972 | 0.69 | SLC6A3 (0.41) | PDE7ALMNAALDH1A1HPGDFBP1 | |
| SCHEMBL12434723 | 0.69 | ADRA1D (0.40) | PDE7AFBP1 | |
| SCHEMBL9036511 | 0.69 | GABRA1 (0.39) | PDE7ALMNAXBP1NPC1ALDH1A1 | |
| SCHEMBL12702042 | 0.69 | FBP1 (0.32) | PDE7AFBP1 | |
| SCHEMBL3198922 | 0.66 | — | — | |
| Carbamic Acid SCHEMBL10928700 | 0.66 | ALOX5 (0.38) | LMNANPC1ALDH1A1HPGDRAB9A | |
| SCHEMBL12394752 | 0.65 | LTB4R (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1009553-B | PREPARATION METHOD OF COMPOUNDS OF 5,6-DIHYDRO-4H-CYOCLOPENTADIENE (B) THIOPHENE-6-CARBOXYLIC ACID | LYON INDUSTRAL MEDICINE CO (FR) | 1990-09-12 | — | — | CN | disclosed |
| CN-85106178-A | 5,6 dihydros-4H-cyclopenta (b) thiophene-6-carboxylic acid compound and contain the preparation method of the medicine of these compounds | — | 1987-03-04 | — | — | CN | disclosed |