Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 6/20 | 0.36 |
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | KIF5B | P33176 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6737417 | 0.98 | TUBB1 (0.39) | TUBB1HTR2AHTR2CHTR2BGAA | |
| SCHEMBL11016445 | 0.82 | TUBB1 (0.40) | TUBB1HTR2AHTR2CHTR2BGAA | |
| SCHEMBL25367240 | 0.81 | ALOX5 (0.41) | TUBB1LMNAMAPK1HTTRAB9A | |
| SCHEMBL6078582 | 0.81 | NPSR1 (0.34) | TUBB1HTR2AHTR2CHTR2BGAA | |
| SCHEMBL167017 | 0.79 | TUBB1 (0.41) | TUBB1HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL8093719 | 0.78 | TUBB1 (0.44) | TUBB1HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL11036235 | 0.77 | NPSR1 (0.40) | HTR2AHTR2CHTR2BGAANPC1 | |
| SCHEMBL27859125 | 0.77 | PDE4A (0.36) | TUBB1HTR2AHTR2CHTR2BLMNA | |
| SCHEMBL25366870 | 0.77 | TUBB1 (0.34) | TUBB1HTR2AHTR2CHTR2B | |
| SCHEMBL29493801 | 0.77 | TUBB1 (0.34) | TUBB1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1013370-B | Process for preparing derivatives of 2, 4, 5-trihalobenzenes and 2, 3, 4, 5-tetrahalobenzenes | BAYER AG (DE) | 1991-07-31 | — | — | CN | disclosed |
| CN-85101737-A | Preparation 2,4,5-trihalogenated benzene and 2,3,4, the derivative method of 5-tetrahalogeno-benzene | — | 1987-01-31 | — | — | CN | disclosed |