SCHEMBL167017

SCHEMBL167017

COc1cc(F)c(F)c(C)c1F

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TUBB1 Q9H4B7 4/20 0.41
ACHE P22303 2/20 0.36
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
RAB9A P51151 1/20 0.34
HTR2A P28223 2/20 0.33
HTR2C P28335 2/20 0.33
HTR2B P41595 2/20 0.33
P2RX7 Q99572 1/20 0.33
KDM1A O60341 3/20 0.33
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
PTGES O14684 1/20 0.32
ALOX5 P09917 1/20 0.32
PTGS1 P23219 1/20 0.32
STAT3 P40763 1/20 0.32
NFE2L2 Q16236 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16071608 0.87 ACHE (0.40) TUBB1ACHEALDH1A1CYP3A4MAPT
SCHEMBL8885005 0.81 TUBB1 (0.41) TUBB1ACHEALDH1A1LMNAMAPK1
SCHEMBL28977384 0.81 TUBB1 (0.39) TUBB1ACHELMNAMAPK1HTT
SCHEMBL8093719 0.80 TUBB1 (0.44) TUBB1ACHEALDH1A1LMNAMAPK1
Methoxymethane SCHEMBL27534547 0.79 CA1 (0.33) TUBB1
SCHEMBL27281163 0.79 TUBB1 (0.40) TUBB1ALDH1A1LMNAMAPK1HTT
SCHEMBL5351315 0.78 TUBB1 (0.38) TUBB1KDM1A
SCHEMBL16137286 0.78 ACHE (0.42) TUBB1ACHEALDH1A1CYP3A4MAPT
Bromide SCHEMBL29739052 0.78 TUBB1 (0.42) TUBB1ALDH1A1LMNAMAPK1HTT
SCHEMBL16071633 0.77 GAA (0.38) TUBB1ACHEALDH1A1LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160329510-A1 PHOTOVOLTAIC CELLS MERCK PATENT GMBH (DE) 2016-11-10 US claimed
EP-3087156-A1 PHOTOVOLTAIC CELLS Merck Patent GmbH (DE) 2016-11-02 EP claimed
WO-2015096886-A1 PHOTOVOLTAIC CELLS MERCK PATENT GMBH (DE) 2015-07-02 WO claimed
EP-2834861-A2 HOLE CARRIER LAYER FOR ORGANIC PHOTOVOLTAIC DEVICE Merck Patent GmbH (DE) 2015-02-11 EP claimed
WO-2013152275-A2 HOLE CARRIER LAYER FOR ORGANIC PHOTOVOLTAIC DEVICE MERCK PATENT GMBH (DE) 2013-10-10 WO claimed
US-20130263925-A1 Hole Carrier Layer For Organic Photovoltaic Device MERCK PATENT GMBH (DE) 2013-10-10 US claimed
EP-3704176-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2024-05-15 EP disclosed
CN-113544186-B Organic semiconductor composition 天光材料科技股份有限公司 2024-03-19 CN disclosed
EP-3794650-B1 ORGANIC SEMICONDUCTORS RAYNERGY TEK INC (TW) 2024-03-13 EP disclosed
US-11930694-B2 Polymer semiconductors containing acrylyl or acrylyl-like side chain and their devices UNIVERSITY OF WATERLOO (CA) 2024-03-12 US disclosed
CN-107915661-B Organic semiconductor compound 天光材料科技股份有限公司 2024-01-23 CN disclosed
CN-112424966-B organic semiconductor 天光材料科技股份有限公司 2023-12-26 CN disclosed
CN-108148073-B Organic semiconductor compound 天光材料科技股份有限公司 2023-12-08 CN disclosed
WO-2006096399-A2 DICARBAZOLE AROMATIC AMINE POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-09-14 WO disclosed
WO-2006060437-A2 SALICYLATE SUBSTITUTED CONJUGATED POLYMERS AND DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 WO disclosed
WO-2006060435-A2 TRIARYLAMINE CONTAINING POLYMERS AND ELECTRONIC DEVICES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-06-08 WO disclosed
EP-1576032-A1 TRICYCLIC ARYLAMINE MONOMER AND POLYMERS AND DEVICES THEREOF Dow Global Technologies Inc. (US) 2005-09-21 EP disclosed
US-6916902-B2 Tricyclic arylamine containing polymers and electronic devices therefrom DOW GLOBAL TECHNOLOGIES INC. (US) 2005-07-12 US disclosed
WO-2004060970-A1 TRICYCLIC ARYLAMINE MONOMER AND POLYMERS AND DEVICES THEREOF DOW GLOBAL TECHNOLOGIES INC. (US) 2004-07-22 WO disclosed
US-20040127666-A1 Tricyclic arylamine containing polymers and electronic devices therefrom DEPARTMENT OF THE NAVY 2004-07-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11930694-B2 Polymer semiconductors containing acrylyl or acrylyl-like side chain and their devices OR10J3, PORCN, OSTC TUBB1 4424/4885ACHE 1938/4885ALDH1A1 1548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.