Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 7/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27279344 | 0.90 | MAPT (0.49) | MAPTNPC1RAB9ALMNAHPGD | |
| SCHEMBL27279424 | 0.88 | CCNE1 (0.41) | MAPTNPC1RAB9ALMNAHPGD | |
| SCHEMBL27279798 | 0.80 | MAPT (0.49) | MAPTNPC1RAB9ALMNAHPGD | |
| SCHEMBL27279783 | 0.79 | MAPT (0.54) | MAPTNPC1RAB9ALMNAHPGD | |
| SCHEMBL27279345 | 0.78 | MAPT (0.43) | MAPTNPC1RAB9ALMNAHPGD | |
| SCHEMBL27280962 | 0.77 | MAPT (0.52) | MAPTNPC1RAB9ALMNAHPGD | |
| SCHEMBL23041102 | 0.77 | EGFR (0.53) | MAPTNPC1RAB9ALMNAPTGS2 | |
| SCHEMBL29769756 | 0.77 | EGFR (0.53) | MAPTNPC1RAB9ALMNAPTGS2 | |
| SCHEMBL5307919 | 0.77 | EGFR (0.53) | MAPTNPC1RAB9ALMNAPTGS2 | |
| SCHEMBL29769749 | 0.77 | EGFR (0.53) | MAPTNPC1RAB9ALMNAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209010-A1 | PRODRUGS OF AZO COMPOUNDS AND THEIR SALTS | AMNEAL PHARMACEUTICALS LLC | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240209010-A1 | PRODRUGS OF AZO COMPOUNDS AND THEIR SALTS | CYP11B1, CYP2C19, CYP11B2 | MAPT 2300/4885NPC1 407/4885RAB9A 2453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.