Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 8/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27392629 | 0.85 | KDM4E (0.64) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL10179413 | 0.85 | KDM4E (0.68) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL24244905 | 0.82 | KDM4E (0.68) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL1585290 | 0.80 | KDM4E (0.83) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL15379923 | 0.79 | NAMPT (0.56) | NAMPTDGAT1CCR1KCNH2HRH3 | |
| SCHEMBL10180063 | 0.79 | GPR119 (0.59) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL13588778 | 0.77 | KCNH2 (0.64) | SMN1; SMN2NAMPTCCR1KCNH2HRH3 | |
| SCHEMBL14151857 | 0.77 | KDM4E (0.97) | KDM4EGLAHTTKMT2ASMN1; SMN2 | |
| SCHEMBL19187763 | 0.76 | NAMPT (0.59) | SMN1; SMN2NAMPTCCR1TLR9TLR8 | |
| SCHEMBL19652150 | 0.75 | CCR1 (0.70) | NAMPTCCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026486-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |