Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.68 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | QDPR | P09417 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.39 |
| ▸ | USP5 | P45974 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27392629 | 0.88 | KDM4E (0.64) | KDM4EL3MBTL1GLAHTTKMT2A | |
| SCHEMBL1585290 | 0.85 | KDM4E (0.83) | KDM4EL3MBTL1GLAHTTKMT2A | |
| SCHEMBL24244905 | 0.85 | KDM4E (0.68) | KDM4EL3MBTL1GLAHTTKMT2A | |
| SCHEMBL27282972 | 0.85 | KDM4E (0.59) | KDM4EL3MBTL1GLAHTTKMT2A | |
| SCHEMBL14151857 | 0.82 | KDM4E (0.97) | KDM4EL3MBTL1GLAHTTKMT2A | |
| SCHEMBL609605 | 0.82 | TRPC6 (0.52) | KDM4EL3MBTL1GLAHTTKMT2A | |
| SCHEMBL30783142 | 0.82 | TRPC6 (0.52) | KDM4EL3MBTL1GLAHTTKMT2A | |
| SCHEMBL10180063 | 0.82 | GPR119 (0.59) | KDM4EL3MBTL1GLAHTTKMT2A | |
| SCHEMBL1577753 | 0.79 | KDM4E (0.42) | KDM4EL3MBTL1GLAHTTKMT2A | |
| SCHEMBL12489379 | 0.78 | FASN (0.47) | KDM4EL3MBTL1GLAHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245344-A1 | GPR119 AGONIST | NIPPON CHEMIPHAR CO., LTD. (JP) | 2012-09-27 | — | — | US | disclosed |
| EP-2474540-A1 | GPR119 AGONIST | Nippon Chemiphar Co., Ltd. (JP) | 2012-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245344-A1 | GPR119 AGONIST | GPR119, GPR4, GPR55 | KDM4E 2502/4885L3MBTL1 1719/4885GLA 3584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.