Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.31 |
| ▸ | MECP2 | P51608 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8349665 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL28121946 | 0.83 | ALDH1A1 (0.47) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL14562749 | 0.82 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL28807262 | 0.82 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL27979361 | 0.82 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL28180007 | 0.82 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL7996476 | 0.82 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL2517442 | 0.82 | ALDH1A1 (0.35) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL28121300 | 0.81 | CYP3A4 (0.50) | ALDH1A1HSD17B10NPC1RAB9AKDM4E | |
| SCHEMBL28121369 | 0.81 | CYP3A4 (0.50) | ALDH1A1HSD17B10NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133474-B2 | Porphyrin chelate compound that may be complexed with zinc, manganese, magnesium, iron or aluminum; capable of insertion into cell; zinc, calcium, mercury, cadmium, and lead analytes; determining shift in signal; medical diagnosis | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-13 | — | — | US | disclosed |
| US-20080138292-A1 | Sensors for fluorescence and magnetic resonance imaging | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138292-A1 | Sensors for fluorescence and magnetic resonance imaging | CA2, SLC30A6, SLC39A3 | ALDH1A1 3462/4885HSD17B10 4304/4885NPC1 383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.