Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.47 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL266817 | 0.77 | EHMT2 (0.62) | EHMT2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4420493 | 0.77 | GPR35 (0.38) | — | |
| SCHEMBL23682885 | 0.75 | EHMT2 (1.00) | EHMT2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31375360 | 0.75 | EHMT2 (0.60) | EHMT2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL17927614 | 0.75 | EHMT2 (0.55) | EHMT2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20135978 | 0.73 | RXFP1 (0.55) | EHMT2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL335983 | 0.73 | SRD5A1 (0.70) | EHMT2RXFP1SRD5A1SRD5A2KMT2A | |
| SCHEMBL15829305 | 0.72 | EHMT2 (0.56) | EHMT2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL25787435 | 0.72 | EHMT2 (0.56) | EHMT2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6514324 | 0.72 | RXFP1 (0.53) | EHMT2RXFP1SRD5A1SRD5A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1008733-B | Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces | PFIZER (US) | 1990-07-11 | — | — | CN | disclosed |
| CN-1007428-B | PROCESS FOR MAKING 2-OXINDOLE-1-CARBOXAMIDES AND INTERMEDIATES THEREFOR | PFIZER (US) | 1990-04-04 | — | — | CN | disclosed |
| CN-1003855-B | Process for preparing 1, 3-disubstituted 2-oxindoles | 美国辉瑞有限公司 | 1989-04-12 | — | — | CN | disclosed |
| CN-85101795-A | With 1, the two 2-oxyindoles that replace of 3-prepare pain killer and antiphlogistic | — | 1987-04-08 | — | — | CN | disclosed |
| CN-85103527-A | Preparation N, the method for the disubstituted 2-hydroxyindole of 3--1-hydroxyalkyl cooh amide | — | 1987-01-28 | — | — | CN | disclosed |
| CN-85101029-A | The method of preparation-2-oxyindole-1-methane amide and intermediate product thereof | — | 1987-01-24 | — | — | CN | disclosed |
| CN-85101028-A | Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces | — | 1987-01-17 | — | — | CN | disclosed |