SCHEMBL2728448

SCHEMBL2728448

COc1ccc(-c2c3ccccc3c(-c3cc(F)c(F)c(F)c3)c3c(F)c(F)c(F)c(F)c23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.44
ACHE P22303 1/20 0.43
ABL1 P00519 1/20 0.38
ABCB1 P08183 1/20 0.38
BCR P11274 1/20 0.38
MAOB P27338 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
ALOX5 P09917 1/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
KDM4E B2RXH2 2/20 0.38
LMNA P02545 2/20 0.38
MAPT P10636 2/20 0.38
ACACA Q13085 1/20 0.38
HTT P42858 1/20 0.38
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPK13 O15264 1/20 0.37
MAPK12 P53778 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2726652 0.91 L3MBTL1 (0.44) L3MBTL1ACHEABL1ABCB1BCR
SCHEMBL2726917 0.91 ACHE (0.51) L3MBTL1ACHEABL1ABCB1BCR
SCHEMBL2725673 0.90 ACHE (0.43) L3MBTL1ACHEABL1ABCB1BCR
SCHEMBL2727043 0.90 L3MBTL1 (0.46) L3MBTL1ACHEABL1ABCB1BCR
SCHEMBL2725454 0.89 ANPEP (0.40) L3MBTL1ACHECA1CA2ALDH1A1
SCHEMBL2726662 0.89 ANPEP (0.39) L3MBTL1ACHEABL1ABCB1BCR
SCHEMBL2711649 0.87 ACHE (0.44) L3MBTL1ACHEABL1ABCB1BCR
SCHEMBL2727061 0.87 MEN1 (0.46) MAOBCA1CA2ALDH1A1HPGD
SCHEMBL2941216 0.87 ACHE (0.43) L3MBTL1ACHEABL1ABCB1BCR
SCHEMBL2728459 0.87 L3MBTL1 (0.36) L3MBTL1ACHEABL1ABCB1BCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
EP-2445987-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS Cyalume Technologies, Inc (US) 2012-05-02 EP disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
WO-2010151654-A1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECHNOLOGIES, INC. (US) 2010-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 L3MBTL1 2477/4885ACHE 187/4885ABL1 1032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.