Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | OAT | P04181 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.41 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27286965 | 0.98 | LMNA (0.49) | TSHRLMNACES2OATGABRR1 | |
| Hydrochloric Acid SCHEMBL27298820 | 0.98 | LMNA (0.49) | TSHRLMNACES2OATGABRR1 | |
| SCHEMBL2874581 | 0.88 | CES2 (0.58) | TSHRLMNACES2OATGABRR1 | |
| SCHEMBL13745963 | 0.88 | CES2 (0.58) | TSHRLMNACES2OATGABRR1 | |
| Bromide SCHEMBL9860546 | 0.86 | CES2 (0.56) | TSHRLMNACES2OATGABRR1 | |
| Hydrochloric Acid SCHEMBL2879189 | 0.86 | CES2 (0.56) | TSHRLMNACES2OATGABRR1 | |
| SCHEMBL12491776 | 0.77 | TSHR (0.54) | TSHRLMNACES2OATGABRR1 | |
| SCHEMBL24471525 | 0.75 | — | — | |
| SCHEMBL10938784 | 0.73 | TSHR (0.46) | TSHRLMNACES2OATGABRR1 | |
| SCHEMBL10938780 | 0.73 | TSHR (0.46) | TSHRLMNACES2OATGABRR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1008737-B | Process for preparing benzo [1] oxy [5] thiacycloheptene derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1990-07-11 | — | — | CN | disclosed |
| CN-85104426-A | Benzo [ 1 ] oxy [ 5 ] thiacycloheptene derivatives, their production and use | — | 1986-04-10 | — | — | CN | disclosed |