Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27287397 | 0.81 | MAPT (0.44) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL4770305 | 0.80 | GAA (0.47) | MAPTGAA | |
| SCHEMBL1246857 | 0.79 | GAA (0.46) | MAPTGAA | |
| SCHEMBL9935465 | 0.73 | MAPT (0.48) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL8334125 | 0.73 | MAPT (0.48) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL8781958 | 0.73 | MAPT (0.48) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL9536334 | 0.73 | GAA (0.48) | MAPTGAA | |
| SCHEMBL27316259 | 0.70 | MAPT (0.41) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL1247317 | 0.69 | MAPT (0.48) | MAPTGAARAB9ASMN1; SMN2 | |
| SCHEMBL11298721 | 0.69 | GAA (0.44) | MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1038099-A | Alpha-adrenergic aceptor antagonist | SMITHKLINE BECKMAN CORP (US) | 1989-12-20 | — | — | CN | disclosed |