Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 4/20 | 0.65 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | DDO | Q99489 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAP2 | P11137 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16767851 | 0.79 | DAO (1.00) | DAODDOGRIN2DGRIN3BGRIN1 | |
| SCHEMBL28984060 | 0.77 | DAO (0.56) | DAOCCNT1CCNE1CDK2CDK9 | |
| SCHEMBL27788007 | 0.77 | AR (0.40) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12476349 | 0.77 | DAO (0.56) | DAOMEN1KMT2ARAB9AKDM4E | |
| SCHEMBL4429400 | 0.76 | SRC (0.43) | MEN1KMT2AKDM4ELMNAALDH1A1 | |
| SCHEMBL29425136 | 0.75 | DAO (0.58) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6161388 | 0.75 | DAO (0.58) | DAOGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30310623 | 0.74 | DAO (0.56) | DAOGRIN1MAP2 | |
| SCHEMBL15822062 | 0.73 | F7 (0.44) | DAOMEN1KMT2ACA12CA9 | |
| SCHEMBL13593176 | 0.73 | DAO (0.55) | DAOGRIN1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1116822-A | Lysine salt of 6-chloro-5-fluoro-3- (2-thenoyl) -2-oxindole-1-carboxamide | PFIZER (US) | 1996-02-14 | — | — | CN | disclosed |
| CN-1099614-A | 6-chloro-5-fluoro-3-(2-thenoyl)-2-oxindole-1-carboxamide as an analgesic and anti-inflammatory agent | PFIZER (US) | 1995-03-08 | — | — | CN | disclosed |
| CN-1008733-B | Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces | PFIZER (US) | 1990-07-11 | — | — | CN | disclosed |
| CN-1003855-B | Process for preparing 1, 3-disubstituted 2-oxindoles | 美国辉瑞有限公司 | 1989-04-12 | — | — | CN | disclosed |
| CN-85101795-A | With 1, the two 2-oxyindoles that replace of 3-prepare pain killer and antiphlogistic | — | 1987-04-08 | — | — | CN | disclosed |
| CN-85101028-A | Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces | — | 1987-01-17 | — | — | CN | disclosed |