Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12476349 | 0.77 | DAO (0.56) | DAOLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL27288077 | 0.77 | DAO (0.65) | DAOLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL20005057 | 0.72 | DAO (0.53) | DAOLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL29425136 | 0.72 | DAO (0.58) | DAOLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL6161388 | 0.72 | DAO (0.58) | DAOLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL16767851 | 0.72 | DAO (1.00) | DAOKDM4EGRIN2DGRIN3BGRIN1 | |
| SCHEMBL30310623 | 0.70 | DAO (0.56) | DAOGRIN1 | |
| SCHEMBL13593176 | 0.69 | DAO (0.55) | DAOLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL21435057 | 0.69 | DAO (0.63) | DAOLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL9233998 | 0.68 | DAO (0.54) | DAOALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960094-A | Preparation and application of aromatic ring substituted methylamine derivative | 上海璎黎药业有限公司 | 2023-04-14 | — | — | CN | disclosed |